Genetics Flashcards

1
Q

human genome

A
  • refers to complete set of genes that an organism possess
  • genome contains 30k-80k genes on 23 pairs of chromosomes
  • small nb of genes = different for different individuals
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Human Genome project

A
  • designed to sequence the entire human genome
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

controversy

A
  • behavioural geneticists attempt to determine the degree to which individual differences are caused by genetic and environmental differences
  • concerns:
    1. ideological concerns: no room for change; suggests plasticity is not present
    2. concerns about renewed interest in eugenics
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

temperament vs trait

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

goals of behavioural geneticists

A
  1. % of individual differences ina trait that can be attributed to genetic differences/envrionmental differences
  2. ways in which genes and environment interact and correlate with each other to produce individual differences
  3. where in the “environment” environmental effects exist
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

T or F? Any trait that we still have has served an adaptive purpose

A

true

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

genotypic variance

A

refers to individual differences in the total collection of genes possessed by each person

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

phenotypic variance

A

refers to observed individual differences, such as height, weight, personality, etc.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

heritability

A

proportion of phenotypic variance that is attributable to genetic variance

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

environmentality

A

proportion of phenotypic variance that is attributable to environmental variance

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

epigenetics

A
  • effect of environment on gene expression
  • silent gene becomes expressed; expressed gene becomes silent
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

heritability misconceptions

A
  • cannot be applied to a single individual
  • not constant
  • not a precise statistic
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

nature vs nurture?

A
  • no such debate at the individual level
  • influences of genes and environment is only relevant for the discussion of group level variation
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

diathesis-stress model

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

selective breeding

A
  • occurs by identifying the dogs that
    possess the desired characteristic and having them mate only with other dogs that also possess the characteristic
  • Dog breeders have been successful precisely because many of the qualities they wish specific dog breeds to have are moderately to highly heritable
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

traditional behavioural genetic methods

A
  • selective breeding studies
  • family studies
  • twin studies
  • adoption studies
17
Q

traditional behavioural genetic methods - selective breeding studies: advantages vs disadvantages

A

advantages:
- can infer heritability if selective breeding works
disadvantages:
- are unethical to conduct on humans

18
Q

traditional behavioural genetic methods - family studies: advantages vs disadvantages

A

advantages:
- provide heritability estimates
disadvantages:
- violate equal environments assumption

19
Q

traditional behavioural genetic methods - twin studies: advantages vs disadvantages

A

advantages:
- provide both heritability and
environmentality estimates
disadvantages:
- sometimes violate equal environments
assumption

20
Q

traditional behavioural genetic methods - adoption studies: advantages vs disadvantages

A

advantages:
- provide both heritability and
environmentality estimates
- get around the problem of equal environments
assumption
disadvantages:
- adopted kids might not be representative of population
- problem of selective placement

21
Q

selective placement

A

if adopted children are placed with
adoptive parents who are similar to their birth parents, then this may inflate the correlations between the adopted children and their adoptive parents

22
Q

do MZ twins seem to be functionally more similar to each other than the environments experienced by the DZ twin?

A

No

23
Q

twin studies

A

if a trait is highly heritable
- family members with greater genetic relatedness should be ore similar to one another on the trait than family members are less closely related
problem:
- members of a family who share the same environment influence the process

24
Q

twin studies: assumptions

A
  1. equal environment assumption
    - because parents provide both genes and environments to their children, and may provide more similar environments for identical than for fraternal twins, there is a potential compromise of the equal environments assumption
  2. representativeness
25
Q

adoption studies

A

genetic parents provide none of the environmental influences on their children, thus unconfounding genetic and environmental causes

26
Q

contrast effect

A
  • children try to be different from siblings
27
Q

birth order effects

A
  • each child experiences parents different
28
Q

Falconer’s formula: calculting heritability

A

2 = 2(rmz - rdz)
refer to p. 168 of textbook

29
Q

major statistical findings in personality

A
  • heritability estimates for major personality traits of about 0.20-0.45
  • some studies suggest as high as 48% across all 5 traits
  • stability of these traits
30
Q

major findings: attitude and preference

A

wide variance in heitability of attitudes

31
Q

major findings: drinking and smoking

A
  • behavioural manifestations of personality traits (sensation seeking, extraversion, neuroticism)
  • drinking alcohol and smoking cigs are stable over time
  • both show evidence of heritability
32
Q

shared vs nonshared environmental influences

A

personality characteristics show heritability in 30-50% range
- hence showing substantial degree of environmentalism (50-70% range)

33
Q

shared vs nonshared environmental influences: types of environmental influences

A
  1. shared
    - in family environement, features of the environment shared by siblings
    - e.g. nb of books in home
  2. nonshared
    - in family environment, features of the environment that differ across siblings
    - e.g. teachers, friends
34
Q

genotype-environment interaction

A
  • differential response of individuals with different genotypes to the same environments (e.g. task performance of introverts vs extraverts in quiet vs noisy conditions)
  • differential exposure of individuals with different genotypes to different environments
  • genotype-environemnt correlations can be + or (passive, reactive, active)
35
Q

passive genotype-environment correlation

A
  • parents provide both genes and environemnt to children, yet children do nothing to obtain that environment
  • e.g. child’s verbal ability and nb of books at home
36
Q

reactive genotype-environment correlation

A
  • parents (or others) respond to children differently depending on child’s genotype
  • e.g. baby’s liking for cuddling and mother’s cuddling
37
Q

active genotype-environment correlation

A
  • person with particular genotypes seek out a particular environment
  • high sensation seekers expose themselves to risky environments