Genetic Variation (PP17) Flashcards
explain Quantitative characters:
vary along a continuum / spectrum within a population
Usually due to polygenic inheritance (additive effects of 2 or more genes influence single phenotypic character)
explain Discrete characters:
generally an either-or
Usually determined by a single locus with different alleles with distinct impacts on the phenotype
explain polymorphism
When 2 or more discrete characters are present & noticeable within a population
polymorphism applies to what characters?
Applies only to discrete characters, not quantitative characters
what are contrasting forms called?`
morphs
give an example of morphs
Red-flowered & white-flowered morphs in a wildflower population, or butterflies
are humans polymorphic
YES
Human populations are polymorphic for a variety of physical (e.g. freckles) & biochemical (e.g. blood types) characters
what does gene diversity measure
Gene diversity: measures average % of gene loci that are heterozygous
what does nucleotide diversity measure
Nucleotide diversity: measures the level of difference in nucleotide sequences (base pair differences) among individuals in a population
what do population genecists measure
Population geneticists measure genetic variation both at the level of whole genes & at the molecular level of DNA
do Humans have relatively little or a lot genetic variation compared to many other organisms
a little
What equation shows Evolution of a population can be explained as changes in allelic frequencies over time
Hardy-Weinberg Equilibrium
If certain conditions are met, allelic (genotypic) frequencies will not change
Genetic frequencies will stabilise to certain proportion:
p2 2pq q2
What conditions does the hardy-weinberg equilibrium need to met.
Large population No mutation (no new alleles) No migration (isolated) No natural selection No sexual selection (random mating)
What happens when all conditions of hardy-weinberg met?
If all of these conditions are met, then we arrive at HW equilibrium:
can a population be in HW equilibrium for 1 locus but not others?
yes
what are genetic frequencies determined by?
Allelic frequencies
LOOK AT SLIDES FOR HARDY WEINBERG EQUATION
LOOK AT SLIDES
explain fitness
fitness = reproductive success of a genotype; generally we think of relative fitness (how well a certain genotype does compared to other genotypes in the same population)
fitness equation
LOOK AT SLIDES
What does the most prolific genotype mean and what fitness (W) does it have?
Most prolific genotype means the one that produces the most offspring
Most prolific genotype is considered to have fitness (W) of 1
what are the two ways of genetic variation
Mutations
-allele resorting
how do you get new alleles
due to changes in nucleotide bases
true or false: Mutations are Continuous, spontaneous, unpredictable, but inducible
-ONly Mutations that are present in gametes will be passed on
true
true
name the ways of allele resorting
- Sexual reproduction (two different parents)
- Segregation of alleles from different parents into different gametes
- Crossing-over
- Random fertilization
explain macroevolution
Large-scale changes in organisms (obvious differences in traits)
These changes are observable only after many generations
explain microevolution
Generation-to-generation change in allele frequency in a population
Generally fairly subtle changes