Genetic Variation

Question 1

what is a population?

Answer 1

spatially discrete units w/ continuous distribution

its the microcosm - encapsulates the larger picture

Question 2

what can be used to define population structures?

Answer 2

quantitative spatial models

Question 3

how can we study population structure?

Answer 3

inbreeding and genetic variation

f-stats and Wahlund effect

Question 4

what is discrete variation?

Answer 4

characteristics controlled by a single gene

• gene and genotype frequencies
• HWC which looks at deriviation and assumptions

Question 5

what are the consequences of inbreeding?

Answer 5

increase of homozygotes w/in a population

Question 6

what is ‘f’?`

Answer 6

the inbreeeding coefficient - a measure of departure from HWC

Question 7

what are the different variables?

Answer 7

Fis - inbreeding w/in subpop/local pop
Fit - inbreeding within overall pop
Fst - (Fit - Fis)/(1-Fis) - differentiation among subpops

Question 8

what happens in local populations?

Answer 8

even if they are in HWC the differences in allele frequency among subpops leads to departure from HWC in pooled pop

Question 9

consequences of inbreeding in terms of genetics?

Answer 9

genotype frequencies change, gene frequencies don’t and neither does genetic variance

Question 10

consequences of inbreeding in terms of genetics with genetic drift?

Answer 10

gene frequencies change and genetic variance decreases