Genetic Material Flashcards
Griffith
1928 - First to identify genetic material - narrowed down to DNA and protein the discovered transformation - he used mice - proved that DNA was the genetic material
Avery
1944 - Repeated Griffiths work and discovered that DNA is the nucleic acid that stores and transmits genetic information from 1 generation to the next
Hershey and Chase
1952 - Used bacteriophages and E-Coli to prove that DNA is the genetic material - they injected phosphorus into the bacterium not the sulfur
Nucleotide
Subunits of nucleic acid
3 parts of a nucleotide
5 carbon sugar
Phosphate group
Nitrogen base
RNA nucleotide
sugar ribose, phosphate, nitrogen bases (adenine, guanine, cytosine, uracil)
DNA nucleotide
deoxyribose sugar, phosphate, nitrogen bases (adenine, guanine, cytosine, thymine)
Chargaff
Found that the amount of guanine equals the amount of cytosine and the amount of adenine equals the amount of thymine
Chargaff’s rule
C=G and T=A
Franklin
Photo 51
Photo 51
indicated that DNA was a double helix
Watson and Crick
Determined that DNA was a shape of a double helix - they used Franklin’s Photo 51
Pyrimidine Bases
Cytosine and Thymine
Purine bases
Adenine and Guanine
purines and pyrimidines
C + T = G + A : 1 purines has to equal 1 pyrimidines - complementary base pairing