genetic info variation and relationship between organisms 3.4 Flashcards
aqa as level biology
what is a genome?
complete set of genes in a cell
what is a proteome?
complete set of proteins a cell can produce
what are the structural differences between mRNA and tRNA
mRNA
- linear single shape
- triplet code (codon)
- less stable
- no amino acid region
tRNA
- clover shaped
- triplet code (anticodon)
- more stable
- amino acid region
what is transcription?
production of mRNA from DNA
what is translation?
production of polypeptides from the sequence of codons carried by mRNA
what happens in transcription?
- DNA helix unwinds to expose bases and on strand acts as a template
- catalysed by DNA helicase
- DNA helicase breaks the hydrogen bonds between bases
- free mRNA nucleotides in the nucleus align with complementary bases on strand
- A/U C/G G/C T/A
- RNA polymerase bonds the nucleotides together to form RNA chain
- once copied mRNA is modified and leaves nucleus through nuclear pores
how is pre-mRNA modified?
- introns are spliced out of pre-mRNA by protein splicesome
- leaves behind just coding regions (exons)
what happens in translation?
- mRNA attaches to ribosome in the cytoplasm
- ribosome attaches at start codon
- tRNA that has complementary anticodon lines up with mRNA codon and binds
- tRNA brings specific amino acid
- amino acids joint together by peptide bonds using ATP (condensation reaction)
- tRNA released after amino acids joint to polypeptide
- ribosome moves along polypeptide until reaches stop codon
- polypeptide formed and now enters Golgi apparatus
what is genetic diversity?
the number of different alleles of genes in a population
what is the enabling factor for natural selection to occur?
genetic diversity
what does natural selection lead to?
evolution
what is evolution?
change in allele frequency over many generations in a population
what are the advantages of natural selection?
leads to species being better adapted to their environment (anatomically, physiologically or behaviourally)
how does natural selection occur?
- random mutations lead to new alleles to form
- if the allele increases the chances of survival in the environment they are more likely to reproduce
- this passes on advantageous allele to offsprings
- over many generations allele frequency increases in population
what is directional selection?
one of the extremes are favoured and have an advantage
when does directional selection occurs?
when there is a change in the environment (modal trait changes)
what is stabilising selection?
modal trait remains the same and is favoured
when does stabilising selection occur?
when there is no change in environment