Genes Lecture 1 Flashcards

1
Q

rise of complex life

A

merging of energy producing alpha photobacterium and information containing Archaea

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2
Q

what was the original cell

A

Loki
discovered in hydrothermal vents in Norway
Asgard-Cell Archaea

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3
Q

telomeres

A

chromatin structure that prevents DNA damage/ degradation during replication

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4
Q

features of telomeres

A

contain loop structures to stop recombining DNA and forming/ fusing with other chromosomes

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5
Q

which cells contain telomerase and why

A

embryonic stem cells, cancer cells and germ cells to prevent chromosomes from getting shorter

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6
Q

how many genomes do eukaryotes have

A

2: nuclear and mitochondrial

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7
Q

features of mitochondrial genomes

A

DNA not bound to histones
small and circular histones
maternal inheritance
similar to a bacterial cell which supports the endosymbiotic model of eukaryotic evolution

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8
Q

intergenic sequences

A

DNA sequences between genes

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9
Q

intragenic sequences

A

DNA sequences within genes e.g. introns

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10
Q

what type of inheritance does mitosis give rise to

A

somatic

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11
Q

mitosis

A

both daughter fells inherit one copy of the duplicated genome

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12
Q

special case of mitosis

A

some cytoplasmic material can be asymmetrically distributed leading to reprogramming of daughter cells

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13
Q

what inheritance does meiosis give rise to

A

germ line

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14
Q

meiosis

A

haploid genome: one copy of the genome and enables sexual reproduction

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15
Q

symmetrical division of mitosis

A

daughter cell

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16
Q

asymmetrical division of mitosis

A

produces differentiated daughter cells and stem daughter cells

17
Q

why is mitosis asymmetrical division beneficial

A

prevents premature exhaustion of adult stem cells such as muscle gut and blood cells

18
Q

karyotypes

A

allows observation of a full set of human chromosomes

19
Q

difference between male and female meiosis

A

have different timings
males produce haploids directly whereas females have an extra step: in meiosis 1: formation of a polar body and in meiosis 2: ejection of a polar body