genes for cancers Flashcards
1
Q
SKT11
A
gastric cancer
2
Q
BRCA1
A
breast and ovarian cancer
3
Q
MLH1 and MSH2
A
MSH2/MLH1 gene mutations are associated with hereditary non-polyposis colorectal carcinoma
HNPCC, an autosomal dominant condition, is the most common form of inherited colon cancer.
4
Q
what cancer is associated with HNPCC
A
endometrial after colon
5
Q
APC
A
familial adenomatous polyposis (FAP) - hundred of polyps
6
Q
are APC mutations a risk factor for desmoid tumours
A
APC mutations are a risk factor for desmoid tumours.
they occur most commonly in women after childbirth in the rectus abdominis muscle.
7
Q
CA-199
A
pancreatic and hepatic cancers
8
Q
C-myc gene
A
Burkitt’s lymphoma (a high-grade B-cell neoplasm).
9
Q
RET oncogene
A
RET oncogene is associated with multiple endocrine neoplasia type II.
