generated by AI -Canine pancreatitis Flashcards
What is elastography?
○ Noninvasive imaging technique
○ Assesses tissue mechanical properties like stiffness
○ Uses sound waves
○ Detects differences in stiffness between healthy and diseased tissues
How was elastography investigated in dogs with suspected acute
pancreatitis?
Shear wave velocity was higher in dogs with suspected AP compared to controls
What is computed tomography angiography (CTA)?
○ Utilizes iodinated contrast material
○ Evaluates blood flow in organs and tissues
○ Rapid image acquisition with multislice CT
What are the imaging findings in acute pancreatitis on CTA?
○ Enlarged pancreas
○ Hypoattenuating appearance
○ Heterogeneous contrast enhancement indicating decreased vascularity
How does CTA compare to abdominal ultrasound in identifying severe acute
pancreatitis and portal vein thrombosis?
○ CTA is superior in identifying severe AP and portal vein thrombosis
What is the sensitivity and specificity of the Spec cPL assay in dogs with
gastrointestinal disease?
○ Sensitivity: 85.7% to 90.9%
○ Specificity: 64.0% to 74.3%
What are some routine clinicopathological features of acute pancreatitis in
dogs?
○ Dehydration reflected by increased PCV and total protein
○ Elevetedtotal protein or Hypoproteinemia due to acute phase response or protein loss
○ Thrombocytopenia from inflammation
○ Left shift in neutrophils
○ Increased acute phase reactants and inflammatory cytokines
How can serum biochemistry profile help in diagnosing acute pancreatitis in
dogs?
○ Azotemia may indicate AKI
○ Increased liver enzyme activities due to hepatic changes
○ Hypocalcemia may occur secondary to other factors
What is the role of symmetric dimethylarginine (SDMA) in detecting acute
kidney injury secondary to acute pancreatitis?
SDMA may be a more sensitive biomarker for AKI secondary to Ap
How can a blood smear evaluation be important in diagnosing acute
pancreatitis in dogs?
Left shift in neutrophils may be present even without increased WBC count
What are some clinical and prognostic findings in dogs with suspected
extrahepatic biliary obstruction and pancreatitis?
What is the role of C-reactive protein in canine acute pancreatitis?
C-reactive protein concentrations may be increased in canine acute pancreatitis,can be used to minitore response to tx
What is the clinical scoring system developed for short-term
prediction of death in dogs with acute pancreatitis?
What are some key recommendations for the diagnosis and management of
canine pancreatitis?
Update on the diagnosis and management of canine pancreatitis
What are some potential applications of experimental models and human
medicine in understanding the pathophysiology of acute pancreatitis in dogs?
Potential applications from experimental models and human medicine to dogs in
understanding the pathophysiology of acute pancreatitis
What is the role of elastography in diagnosing acute pancreatitis in dogs?
Elastography is a noninvasive imaging technique that can detect differences in tissue
stiffness between healthy and diseased tissues
How does computed tomography angiography (CTA) help in evaluating acute
pancreatitis in dogs?
CTA utilizes iodinated contrast material to better evaluate blood flow in organs and
surrounding tissues, providing detailed imaging of the pancreas in cases of acute
pancreatitis
What are some of the routine clinicopathological features that can aid in the
diagnosis of acute pancreatitis in dogs?
● CBC findings reflecting dehydration and inflammation
● Serum biochemistry profile showing hepatic changes and potential kidney injury
● Evaluation of acute phase reactants and inflammatory cytokines
How can the integration of clinical signs, laboratory findings, and imaging
techniques aid in the effective diagnosis of acute pancreatitis in dogs?
Integration of clinical signs, laboratory data, and imaging findings is essential for an
accurate diagnosis of acute pancreatitis due to the nonspecific nature of clinical signs
