AI generated questions Triaiditis in cats Flashcards

1
Q

What is feline triaditis?

A

○ Concurrent presence of pancreatitis, cholangitis, and inflammatory bowel disease
(IBD) in cats.

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2
Q

What are the potential causes of feline triaditis?

A

○ Infectious, autoimmune, or physical factors like duct obstruction.
○ Anatomy of the feline gastrointestinal tract, including a short small intestine and
high bacterial load in the duodenum, may contribute.

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3
Q

How does feline gastrointestinal tract anatomy contribute to triaditis?

A

○ Short small intestine and high bacterial load in the duodenum increase the risk of
bacterial reflux and parenchymal inflammation.
○ Anatomical feature where the pancreatic duct joins the common bile duct before
entering the duodenal papilla plays a role.

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4
Q

What are the diagnostic challenges associated with identifying pancreatitis in
cats?

A

○ Diagnosis based on increased serum pancreatic lipase immunoreactivity or feline
pancreas-specific lipase.
○ Abnormal pancreatic changes on ultrasonography, but tests have low sensitivity.

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5
Q

How is cholangitis diagnosed in cats?

A

○ Accompanied by increased serum liver enzymes, total bilirubin, and bile acid
concentrations.
○ Variable ultrasonographic changes may be present.

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6
Q

What are the challenges in diagnosing IBD in cats?

A

○ Diagnosis challenging without histopathology.
○ Ultrasound findings can vary from normal to mucosal thickening or loss of
layering.

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7
Q

How is triaditis confirmed in cats?

A

○ Requires histopathology from each affected organ.
○ Often remains a presumptive diagnosis due to the need for histopathological
assessment.

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8
Q

What is the importance of early and appropriate medical therapy in managing
feline triaditis?

A

○ Crucial for effective management of the condition.
○ Tailored treatment based on the specific type and severity of disease in each
affected organ.

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9
Q

How does feline gastrointestinal tract anatomy contribute to the development
of triaditis?

A

○ Short small intestine and high bacterial load in the duodenum increase the risk of
bacterial reflux.
○ Anatomical feature where the pancreatic duct joins the common bile duct before
entering the duodenal papilla plays a role.

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10
Q

What are the diagnostic challenges associated with identifying pancreatitis in
cats?

A

○ Diagnosis based on serum pancreatic lipase immunoreactivity or feline pancreas-
specific lipase.
○ Ultrasonography may show abnormal pancreatic changes, but tests have low
sensitivity.

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11
Q

How is cholangitis diagnosed in cats?

A

○ Increased serum liver enzymes, total bilirubin, and bile acid concentrations may
be present.
○ Ultrasonographic changes can vary.

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12
Q

What are the challenges in diagnosing IBD in cats?

A

○ Diagnosis difficult without histopathology.
○ Ultrasound findings may range from normal to mucosal changes.

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13
Q

How is triaditis confirmed in cats?

A

○ Requires histopathology from each affected organ.
○ Often remains a presumptive diagnosis due to the need for histopathological
assessment.

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14
Q

What is the importance of early and appropriate medical therapy in managing
feline triaditis?

A

○ Crucial for effective management.
○ Treatment should be tailored based on the specific disease severity in each
affected organ.

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15
Q

What are the key points regarding feline triaditis?

A

○ Concurrent presence of pancreatitis, cholangitis, and IBD.
○ Prevalence ranges from 17% to 39% in ill referral patients.

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16
Q

What role does feline gastrointestinal tract anatomy play in triaditis?

A

○ Short small intestine and high bacterial load increase the risk of bacterial reflux.
○ Anatomical feature where the pancreatic duct joins the common bile duct
contributes to parenchymal inflammation.

17
Q
A
18
Q

What are the key considerations in managing feline triaditis?

A

○ Early and appropriate medical therapy is crucial.
○ Treatment should be tailored to the specific type and severity of disease in each
affected organ.

19
Q

What is the prognosis for cats with triaditid?

A

AThe prognosis for cats with triaditis depends on the severity of their disease. Cats
with mild disease can be treated on an outpatient basis and have a good prognosis.
However, cats with acute severe disease, especially with systemic complications, may
have a poor prognosis and require more aggressive therapy. Risk factors such as
hypoalbuminemia, hypoglycemia, and systemic hypotension can indicate severe and life-
threatening disease. Successful management of all concurrent conditions is crucial for a
better outcome, as many affected cats develop chronic signs of illness with recurrent
episodes of triaditis over time. Appropriate management is important for decreasing the
risk of potentially severe consequences, such as chronic pancreatitis leading to exocrine
pancreatic insufficiency or diabetes, severe cholangitis leading to cholangiohepatitis or
gallstones, and chronic lymphoplasmacytic IBD leading to enteric lymphoma.

20
Q

What are the treatment recommendations for cats with triaditis?

A

○ Tailored treatment based on the specific disease severity in each affected organ.
○ Outpatient treatment for mild cases; hospitalization and aggressive therapy for
severe cases.

21
Q

How does intravenous fluid therapy benefit cats with triaditis?

A

○ Ensures hydration and adequate organ perfusion.
○ Corrects dehydration, maintains fluid balance, and replaces ongoing losses.

22
Q

○ Ensures hydration and adequate organ perfusion.
○ Corrects dehydration, maintains fluid balance, and replaces ongoing losses.

A

○ Hypokalemia and hypocalcemia.
○ Monitoring and correction are essential for patient management.

23
Q

How can hypokalemia be corrected in hospitalized cats with triaditis?

A

○ Parenteral administration of potassium chloride in intravenous fluids.
○ Oral supplementation may also be used in some cases.

24
Q

Why is antiemetic therapy important in the treatment of triaditis in cats?

A

○ Helps manage nausea and vomiting, which can lead to complications.
○ Even intermittent vomiting can indicate underlying nausea in cats.

25
Q

What are the potential complications of severe triaditis in cats?

A

○ Systemic complications like hypotension, hepatic encephalopathy, coagulopathy,
vasculitis, and disseminated intravascular coagulation.
○ These complications can worsen the prognosis and require aggressive therapy.

26
Q

What are the negative prognostic indicators in feline patients with triaditis?

A

○ Hypoalbuminemia, hypoglycemia, and systemic hypotension.
○ These factors indicate severe and life-threatening disease.

27
Q

How does successful management of all concurrent conditions impact the
prognosis of cats with triaditis?

A

○ Crucial for a better outcome.
○ Helps decrease the risk of potentially severe consequences and recurrent
episodes of triaditis.

28
Q

What are the potential long-term consequences of chronic pancreatitis in cats
with triaditis?

A

○ Exocrine pancreatic insufficiency and/or diabetes.
○ Chronic pancreatitis can predispose cats to these conditions.

29
Q

How can chronic/severe cholangitis in cats with triaditis lead to complications?

A

○ Predisposes to cholangiohepatitis, gallstones, chronic biliary cirrhosis, and
possibly cholangiocarcinoma.
○ Long-term consequences of cholangitis in affected cats.

30
Q

What are the potential consequences of chronic lymphoplasmacytic IBD in cats
with triaditis?

A

○ Predisposition to enteric lymphoma.
○ Long-term implications of IBD in cats with triaditis.

31
Q

: What is the significance of understanding the natural history and aetiology of
triaditis in cats?

A

○ More studies needed for better understanding.
○ Helps in diagnosing all component parts, determining effective treatments, and
identifying important prognostic factors.

32
Q

What are the key areas that require further study regarding feline triaditis?

A

○ Understanding which organs can be affected by the inflammatory process.
○ Improving diagnostic methods, treatment effectiveness, and prognostic factors.

33
Q

How can a treatment algorithm benefit feline patients with triaditis?

A

○ Provides a structured approach to managing the condition.
○ Helps in tailoring treatment based on the specific disease severity in each
affected organ.

34
Q

What are the recommendations for managing cats with mild clinical signs of
triaditis?

A

○ Outpatient treatment for hemodynamically stable cats.
○ Close monitoring and appropriate therapy to prevent complications.

35
Q

What are the indications for hospitalization in cats with severe clinical signs of
triaditis?

A

○ Severe clinical signs requiring aggressive therapy.
○ Hospitalization for fluid therapy, analgesics, antiemetics, and assisted feeding to
prevent hepatic lipidosis.

36
Q

How does vomiting contribute to the spread of enteric bacteria in cats with
triaditis?

A

○ Vomiting can cause reflux of duodenal juice into the pancreas and bile duct.
○ Spreads enteric bacteria into the pancreas and biliary tree, contributing to
inflammation.

37
Q

What are the potential routes of bacterial colonization in cats with pancreatitis
and hepatic diseases?

A

○ Reflux from the intestinal tract into the pancreatic duct.
○ Haematogenous spread and translocation across the mucosal barrier into the
portal blood circulation.

38
Q

How does the anatomy of the feline gastrointestinal tract increase the risk of
bacterial reflux in cats with triaditis?

A

○ Short small intestine and high bacterial load in the duodenum.
○ Anatomical features facilitate the ascent of bacteria into the liver and pancreas,
leading to inflammation.

39
Q

What are the common enteric species isolated from the pancreas and liver of
cats with pancreatitis and hepatic diseases?

A

○ E. coli and other enteric bacteria.
○ Support the theory of bacterial reflux contributing to parenchymal inflammation
in affected organs.