Generalities Flashcards

1
Q

All viruses have

A

Protein coat (capsid)

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2
Q

All helical viruses have

A

Envelope

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3
Q

All enveloped viruses acquire their envelope from plasma membrane, EXCEPT

A
Herpes Virus (HSV, HHV, VZV, CMV, EBV)
Nuclear membrane
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4
Q

All viruses are haploid EXCEPT

A

Retroviruses (2 copies of positive sense single stranded RNA)

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5
Q

All viruses contain EITHER DNA or RNA, except

A

Mimivirus

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6
Q

Segmented viral genome: BOAR

A

Bunya
Orthomyxo (influenza)
Arena
Reo (rota)

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7
Q

Negative stranded RNA:
Always Bring Polymerase Or Fail Replication
(BOARha-PF)

A
Bunya
Orthomyxo - influenza
Arena
RHAbdo - rabies
Parmyxo - pedia
Filoooooo - ebola
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8
Q

Live attenuated vaccines

MMR bawal Sa PregnanCY

A
MMR
Smallpox
Polio (Sabin)
Chicken pox
Yellow fever
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9
Q

Killed vaccines

RIP-A

A

Rabies
Influenza
Polio (salK’s)
A hepa

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10
Q

Only virus with fiber (penton fiber)

A

Adenovirus
ds, linear DNA virus
with icosahedral nucleocapsid

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11
Q

Intranuclear inclusion bodies
Cowdry type A
Cowdry type B
Owl’s eye

A

Type A: HSV, VZV
Type B: Adeno, Polio
Owl’s eye: CMV

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12
Q

Most common viral STD

A

Condylomata accuminata
Genital warts
hPV 6&11

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13
Q

MC cause of infection in organ transplant patients
MC INFECTIOUS* cause of congenital abnormalities
MC cause of blindness in AIDS patients

A

CMV

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14
Q

Intracytoplasmic inclusions:
Guarnieri bodies
Henderson-Peterson Bodies
Negri bodies in nerve cells

A

Small pox (Variola) - also seen in nuclei
Molluscum contagiosum
Rabies

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15
Q

1st viral vaccine to prevent cancer

A

HBV vaccine

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16
Q

MCC of mycocarditis, pancarditis

A

Coxsackie virus type B

17
Q

MCC of aseptic meningitis

A

Enteroviruses (3 PEC)

18
Q

2 viral causes for common colds

A

Rhinovirus

Coronavirus

19
Q
MC cause of nonbacterial diarrhea in adults
Viral gastroenteritis (with fever) after eating contaminated seafoods
A

Norwalk virus

20
Q

MC cause of childhood diarrhea

21
Q

Multinucleated giant cells

Warthin-Finkeldey Bodies

A

Measles

Caused by fusion protein in spike

22
Q

Spots
Kopliks spots
Nagayama spots
Forscheimer spots

A

Measles
Roseola
Rubella

23
Q

Most important cause of pneumonia and bronchiolitis in infants

24
Q

Most prevalent blood-borne pathogen

IV drug abusers

25
Main cause of essential mixed cryoglobulinemia
HCV
26
MCC of liver transplantation
Chronic HCV infection leading to liver cirrhosis
27
MCC of endemic encephalitis Transmitted by mosquito Location of infarct?
Japanese B virus (flaviviridae) Transmitted by culex mosquito Thalamic brain infarcts