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Virology > Generalities > Flashcards

Generalities Flashcards

1
Q

All viruses have

A

Protein coat (capsid)

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2
Q

All helical viruses have

A

Envelope

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3
Q

All enveloped viruses acquire their envelope from plasma membrane, EXCEPT

A 
Herpes Virus (HSV, HHV, VZV, CMV, EBV)
Nuclear membrane
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4
Q

All viruses are haploid EXCEPT

A

Retroviruses (2 copies of positive sense single stranded RNA)

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5
Q

All viruses contain EITHER DNA or RNA, except

A

Mimivirus

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6
Q

Segmented viral genome: BOAR

A

Bunya
Orthomyxo (influenza)
Arena
Reo (rota)

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7
Q

Negative stranded RNA:
Always Bring Polymerase Or Fail Replication
(BOARha-PF)

A 
Bunya
Orthomyxo - influenza
Arena
RHAbdo - rabies
Parmyxo - pedia
Filoooooo - ebola
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8
Q

Live attenuated vaccines

MMR bawal Sa PregnanCY

A 
MMR
Smallpox
Polio (Sabin)
Chicken pox
Yellow fever
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9
Q

Killed vaccines

RIP-A

A

Rabies
Influenza
Polio (salK’s)
A hepa

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10
Q

Only virus with fiber (penton fiber)

A

Adenovirus
ds, linear DNA virus
with icosahedral nucleocapsid

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11
Q

Intranuclear inclusion bodies
Cowdry type A
Cowdry type B
Owl’s eye

A

Type A: HSV, VZV
Type B: Adeno, Polio
Owl’s eye: CMV

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12
Q

Most common viral STD

A

Condylomata accuminata
Genital warts
hPV 6&11

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13
Q

MC cause of infection in organ transplant patients
MC INFECTIOUS* cause of congenital abnormalities
MC cause of blindness in AIDS patients

A

CMV

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14
Q

Intracytoplasmic inclusions:
Guarnieri bodies
Henderson-Peterson Bodies
Negri bodies in nerve cells

A

Small pox (Variola) - also seen in nuclei
Molluscum contagiosum
Rabies

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15
Q

1st viral vaccine to prevent cancer

A

HBV vaccine

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16
Q

MCC of mycocarditis, pancarditis

A

Coxsackie virus type B

17
Q

MCC of aseptic meningitis

A

Enteroviruses (3 PEC)

18
Q

2 viral causes for common colds

A

Rhinovirus

Coronavirus

19
Q 
MC cause of nonbacterial diarrhea in adults
Viral gastroenteritis (with fever) after eating contaminated seafoods
A

Norwalk virus

20
Q

MC cause of childhood diarrhea

A

Rotavirus

21
Q

Multinucleated giant cells

Warthin-Finkeldey Bodies

A

Measles

Caused by fusion protein in spike

22
Q

Spots
Kopliks spots
Nagayama spots
Forscheimer spots

A

Measles
Roseola
Rubella

23
Q

Most important cause of pneumonia and bronchiolitis in infants

A

RSV

24
Q

Most prevalent blood-borne pathogen

IV drug abusers

A

Hepa C

25
Q

Main cause of essential mixed cryoglobulinemia

A

HCV

26
Q

MCC of liver transplantation

A

Chronic HCV infection leading to liver cirrhosis

27
Q

MCC of endemic encephalitis
Transmitted by mosquito
Location of infarct?

A

Japanese B virus (flaviviridae)
Transmitted by culex mosquito
Thalamic brain infarcts

Virology (4 decks)

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