generalised oedema Flashcards
nephrotic syndrome causes
not inflamamtory
damage to podocytes
minimal change glomerulonephritis
FSGN
hall mark of nephrotic syndrome
hypoalbuminemia
albuminuria
hyperlipidemia
oedema - eyes worst mornings
hx assocaited with nephrotic syndrome
welling/puffy in morning esp eyes pitting oedema wt gain thirsty
CF of nephrotic syndrome
hypotension
pleural effusion
pedal oedema
ascites
ix for nephrotic syndrome
urine dip - ++++ prot, no blood (20% do) lipids - increased chol LFT - low alb UEC - normal FBC - increased Hct Ig - decreased
mx of nephrotic syndrome
IVF if hypotension management fluid overload if apparent prednisolone 4 wks then wean albumin penicillin - risk of SBP ?aspirin - hypercoagulable
prognosis of nephrotic syndrome
90% fully recover, 50% steroid dependent
cx of nephrotic syndrome
hypotension
SBP
ascites, pleural effusion
causes of nephritic syndrome
PSGN
IgA
hallmarks of nephritic syndrome
HTN
proteinuria - non seclective
oliguria
oedema
hx associated with nephritic syndrome
skin/throat infections loin pain headache oliguria haematuria
ix nephritic syndrome
urine - haematuria, proteinuria non selective, casts
ASOT, anti-DNAse B
UEC - raised creatinine
C3 - low
mx nephritic syndrome
fluid restrict
frusemide if overloaded
daily weights
+/- penicillin
prognosis of nephritic syndrome
most fully recovery
cx of nephritic syndrome
ARF
CRF
severe electrolyte imbalances
cx of HTN - stroke, pulmonary oedema, encephalopathy