General: Opthalmology Flashcards
What conditions should you be able to diagnose and treat?
Common causes of a red eye
What conditions should you be able to recognise and refer on?
Painful, red eye
Loss of vision
Double vision
Eyelid problems
What are some causes of lid lump?
Stye Chalazion Basal cell carcinoma (rodent ulcer) Molluscum contagiosum (umbilicated lesions) Papilloma Squamous cell carcinoma Keratoaanthoma
What are some causes of red eye?
Benign: Conjunctivitis Blepharitis Dry Eye Episcleritis
Dangerous: Acute angle glaucoma Iritis Disthyroid eye disease Corneal ulcer AML (acute leukemic retinopathy)
Do you need to manage loss of vision?
No, just refer
What is gradual loss of vision?
Days, weeks, months
Degenerative, neuropathic, vasculopathy
What is sudden vision loss?
Seconds, minutes, hours
Inflammatory, vascular occlusion, haemorrhage
(can be just noticed visual loss - happen to shut good eye)
What do you need to do for visual loss examination? (5)
- History: onset, distortion, PMH, pain
- Assess vision: mild, moderate or proound loss.
- Test pupil for relative afferent pupil defect
- Test field for central scotoma or hemianopia
- Ask about colour vision (optic neuritis)
What are causes of distorted vision?
Retinal detachment
Macular degeneration
Diabetic retinopahty
Get advice quickly
What causes of the gradual onset visual loss are there? (5)
Gradual onset
- Cataract
- Chronic glaucoma
- Macular degeneration
- Optic nerve compression: RAPD
- Glasses requirement
What are some of the sudden causes of visual loss? (5)
- Ischaemic optic neuropathy (PMR/GCA)
- Retinal detachment (flashes, floaters, field loss)
- Vitreous haemorrhage
- Vascular occlusion (artery and vein, branch and central, abrupt and variable)
- Acute glaucoma
Other causes of visual loss? (2)
- Optic/retrobulbar neuritis
2. Diabetic retinopathy (screened for)
What visual defects should you know about?
Homonymous hemianopia (vascular or tumor)
Bitemporal hemianopia (usually tumour)
Central scotoma
Transient visual loss (papilloedema, GCA, TIA)
What is Argyll-Robertson pupil?
Classic pupillary syndrome
Prostitutes Pupil -
Accomodation reflex present but pupillary reflex absent
Small irregular pupils, no response to light but a response to accomodation
What conditions is Argyll-Robertson pupil seen in?
Diabetes mellitus
Neurosyphilis
What is an entropion?
In-turning of the eyelids
What is an ectropion?
Out-turning o the eyelids.
What is Herpes Zoster Ophthalmicus (HZO)?
Describes the reactivation of the varicella-zoster virus (shingles) in the area supplied by the opthalmic devision of the trigeminal nerve. (10% cases)
What are the features of Herpes Zoster Ophthalmicus (HZO)?
Vesicular rash around the eye, which may or may not involve the actual eye itself
What is Hutchinson’s sign in Herpes Zoster Ophthalmicus (HZO)?
A rash on the tip or side of the nose. Indicates nasociliary involvement and is a strong risk factor for ocular involvement.
What is the management of Herpes Zoster Ophthalmicus (HZO)?
Oral antiviral treatment for 7-10 days (IV if immunocompromised)
Topical corticosteroids for eye inflammation
Ocular involvement requires urgent opthalmology review
What are the complications of Herpes Zoster Ophthalmicus (HZO)?
Ocular: conjunctivitis, keratitis, episcleritis, anterior uveitis
Ptosis
Post-herpetic neuralgia
What is Holmes-Adie pupil?
A benign condition most commonly seen in women.
Differential of a dilated pupil
Unilateral in 80% of cases
Dilated pupil
Once the pupil has constricted it remains small for an abnormally long time
Slowly reactive to accommodation but very poorly (if at all) to light
What is Holmes-Adie syndrome
Association of Holmes-Adie pupil with absent ankle/knee reflexes
What is Horner’s syndrome?
Miosis (small pupil)
Ptosis
Enopthalmos (sunken eye)
Anhidrosis (loss of sweating one side)
What is seen in congenital Horner’s syndrome?
Heterochromia (difference in iris colour)
When Horner’s syndrome is caused by central lesions, what form of anhidrosis is seen?
Anhidrosis of the face, arm and trunk
When Horner’s syndrome is caused by pre-ganglionic lesions, what form of anhidrosis is seen?
Anhidrosis of the face
When Horner’s syndrome is caused by post-ganglionic lesions, what form of anhidrosis is seen?
No anhidrosis
What are the central lesion causes of Horner’s syndrome?
S
Stroke Syringomyelia Multiple Sclerosis Tumour Encephalitis
What are the pre-ganglionic lesion causes of Horner’s syndrome?
T
Pancoast’s Tumour
Thyroidectomy
Trauma
Cervical rib
What are the post-ganglionic lesion causes of Horner’s syndrome?
C
Carotid artery dissection
Carotid aneurysm
Cavernous sinus thrombosis
Cluster headache
What classification is used in Hyperetensive Retinopathy?
Keith-Wagener classfication
What is stage I of the Keith-Wagener classification of hypertensive retinopathy?
Arteriolar narrowing and tortuosity
Increased life reflex - silver wiring
What is stage II of the Keith-Wagener classification of hypertensive retinopathy?
Arteriovenous nipping
What is stage III of the Keith-Wagener classification of hypertensive retinopathy?
Cotton-wool exudates
Flame and blot haemorrhages
What is stage IV of the Keith-Wagener classification of hypertensive retinopathy?
Papilloedema
What is mydriasis?
Dilated pupil
What are the physiological causes of mydriasis?
Third nerve palsy Holmes-Adie pupil Traumatic iridoplegia Phaeochromocytoma Congenital
What are the drug causes of mydriasis?
Topical mydriatics: tropicamide, atropine
Sympathomimetic drugs: amphetamines, cocaine
Anticholinergic drugs: tricyclic antidepressants
What is aniscoria?
Difference in sizes of pupils
What is nasolacrimal duct obstruction?
Most common cause of a persistent watery eye in an infant.
Caused by an imperforate membrane, usually at the lower end of the lacrimal duct.
1/10 infants
What is the management of nasolacrimal duct obstruction?
Teach parents to massage lacrimal duct
95% will resolve by 1 y/o
What is hyphema?
Blood in the anterior chamber (water-line iris appearance)
In the context of trauma warrants urgent referral to an ophthalmic specialist for assessment and management.
What is the main risk to sight in hyphema?
Raised ICP due to blockage of the angle and trabecular meshwork with erythrocytes
What is the treatment of hyphema?
Strict bed rest to prevent redistribution of settled blood
High risk cases may be admited
What is optic neuritis?
Occurs when swelling damages the optic nerve
Presents as pain with eye movement
Sudden temporary unilateral decrease in visual acuity (visual loss) over hours or days
Poor discrimination of colours - red desaturation
Relative afferent pupillary defect
Central scotoma
What are the causes of optic neuritis?
Multiple sclerosis
Diabetes
Syphilis
What is the management of optic neuritis?
High-dose steroids
Recovery usually takes 4-6 weeks
What is the prognosis of optic neuritis?
> 3 white-matter lesions, 5-year risk of developing multiple sclerosis is 50%
What is papilloedema?
Optic disc swelling that is caused by increased intracranial pressure.
Almost always bilateral.
What is seen on fundoscopy in papilloedema?
Venous engorgement: first sign Loss of venous pulsation Blurring of the optic disc margin Elevation of optic disc Loss of optic cup Paton's lines: concentric/radial retinal lines cascading from the optic disc
What are the causes of papilloedema?
Space-occupying lesion: neoplastic, vascular Malignant hypertension Idiopathic intracranial hypertension Hydrocephalus Hypercapnia
Rare:
Hypoparathyroidism
Hypocalcaemia
Vitamin A toxicity
What is Endopthalmitis?
Endophthalmitis is a purulent inflammation of the intraocular fluids (vitreous and aqueous) usually due to infection.
Red-eye, pain and visual loss typically following intraocular surgery.
What is Relative afferent pupillary defect?
Also known as the Marcus-Gunn pupil, found by the swinging light test.
What is the cause of a Relative afferent pupillary defect?
A lesion anterior to the optic chiasm i.e. optic nerve or retina.
Causes:
Retina: Detachment
Optic nerve: Optic neuritis
What is seen on a swinging light test in a Relative afferent pupillary defect?
The affected and normal eye appears to dilate when light is shone on the affected eye.
What is the pathway of the afferent pupillary light reflex?
Afferent: retina → optic nerve → lateral geniculate body → midbrain
What is the pathway of the efferent pupillary light reflex?
Efferent: Edinger-Westphal nucleus (midbrain) → oculomotor nerve
What are the most common causes of sudden painless loss of vision?
Ischaemic/vascular (thrombosis, embolic, temporal arteritis), occlusion of central retinal vein and artery.
Vitreous haemorrhage
Retinal detachment
Retinal migraine
What are the ischamic/vascular causes of sudden visual loss?
Wide differential
Atherothrombosis, embolus, dissection, anterior ischamic optic neuropathy, vasculitis, temporal arteritis, venous disease, hypoperfusion, TIA
Curtain coming down
TIA - aspirin 300mg
What are the causes of tunnel vision?
Papilloedema Glaucoma Retinitis pigmentosa Choroidoretinitis Optic atrophy secondary to tabes dorsalis Hysteria