General metabolism Flashcards
How many carbons are removed per cycle of B-oxidation of fatty acids?
2
acetyl coA
Which foetal organs make up the feto-placental unit?
Adrenal
Liver
Placenta
What the difference between cystine and cysteine?
Cysteine is a single amino acid
Cystine is two bound together by a disulphide bond
What is the general function of creatine? How?
Acts as a store of ATP in skeletal muscle
When levels of ATP are high in muscles, what is it stored as?
Creatine phosphate
When atp is low in muscles what is quickly broken down to form ATP?
Creatine phosphate to form creatine and ATP
What is used as clinical marker of urine dilution?
Creatinine
What can creatinine be a clinical marker for?
Muscle mass and urine dilution
How is creatinine used to assess urine dilution?
Concentration of creatinine is compared to standard- if low TF shows dilute urine, high shows conc urine
What is used as a clinical marker for MI’s?
Creatine kinase
How do creatine kinase levels show MI?
Not normally present in blood, one isoform is specific to the heart muscle, if in blood shows muscle damage
What bonds are present in glycogen?
Alpha 1-4 glycosidic and alpha 1-6 glycosidic
What enzymes form which bonds in glycogen?
Glycogen synthase forms alpha 1-4, branching enzyme forms alpha 1-6
