General Last minute Flashcards
Mechanism of antirheumatic drugs
Methotrexate
Leflunomide
Etanercept
Infliximab
Adalimumab
Anakinra
Methotrexate - antifolate
Leflunomide - pyrimidine modulator
Etanercept - anti TNF
Infliximab - anti TNF
Adalimumab - anti TNF
Anakinra - Anti IL-1
Mechanism of common antibiotics
Clindamycin
Gentamycin & Tobramycin
Ciprofloxacin
Septra
Penicillin
Vancomycin
Cephalosporins
Clindamycin - blocks protein synth (50s subunit)
Gentamycin & Tobramycin - blocks protein synth (30s)
Ciprofloxacin - Inhibits DNA synthesis
Septra - inhibits folic acid synthesis
Penicillin - inhibits cell wall synthesis
Vancomycin - inhibits cell wall synthesis
Cephalosporins - inhibits cell wall synthesis
Genetics of dysplasias
Most are AD inherited. Name two that are AR and one that is XLR
AR
Diastrophic dysplasia
McKusick metaphyseal dysplasia
XLR
SED tarda (congenita is AD)
Name 2 things that are sex linked Dominant?
Familial hypophosphatemic rickets
Leri-Weill dyschondrosteosis
4 components of Constant Score
Pain
Function
Strength
ROM
3 components of WOMAC
Pain
Stiffness
Physical function
Radiographic signs of a posterior shoulder dislocation
Lightbulb sign
Anterior rim sign (>6mm from medial humerus to anterior glenoid)
Trough sign
Order of return of nerve function
Sympathetic
Pain
Temperature
Light Touch
Proprioception
Motor
Medial knee layers
- Sartorius fascia
- sMCL, POL, semimembranosus, MPFL
- dMCL, capsule
2 things made of type 2 collagen
Hyaline cartilage
nucleus pulposis
PTH normal in 2 things
Hypophosphatasia
Vit D resistant (Hypophosphatemic) Rickets
ALP very decreased in one thing
Hypophosphatasia
Phosphate up in 2 things
Hypophosphatasia (yes, weird)
Renal osteodystrophy
