General Flashcards
left ventricular end-diastolic volume
150mL
LV-end systolic volume
50mL
Stroke volume
100mL
Ejection fraction
67%
LV end-diastolic pressure
10mmHg
LV systolic
130mmHg
RA pressure
3 mmHg
RV systolic pressure
25mmHg
LA pressure
8mmHg
pre-load determined by…
End diastolic pressure or volume
Frank-Starling mechanism
The greater the EDV (pre-load), the greater the force of contraction
the resistance ventricle must overcome to pump out its contents
afterload/ systollic ventricular wall tension or stress
Ventricular wall stress (afterload) is equal to…
ventricular pressure X ventricular chamber radius
divided by
2 X ventricular wall thickness
Pvent X r
2 X wall thickness
**Laplace relationship
As arterial blood pressure in aorta (or pulmonary trunk) goes up…
Stress increases proportionately
The greater the ventricular wall thickness (within physiologic range)…
The less stress