General Flashcards
4 cell types of nervous system
Neurons
Astrocytes
Oligodendrocytes (Schwann cells)
Microglia
Neuron AP resting level
-70mV
Neuron AP threshold
-50mN
What is responsible for the electrical properties of neurons?
ion channels
White matter composition
budles of myelinated axons
Grey matter composition
cell somata, dendrites and synapses
Where are most synapses?
On dentritic spines
Nt of inhibitory synapses
GABA
Nt of excitatory synapses
Glutamate
Nt of modulatory synapses
serotonin, NE, dopamine, neuropeptides
Dopamine neuromodulators location
Substania nigra and ventral tegmental area
Pathology orientation
Left Right
Radiology orientation
Right Left
Afferent
Going to the brain
Efferent
Going to muscles
Global mental health burden
0.5% death
7.4% disability adjusted life years
22.9% of years lived with disability
(depression, anxiety disorders, substance/alcohol abuse and schizophrenia are the main causes)
higher prevalence in mental health illness
high income english speaking countries
ICD
International Classification of Diseases
DSM
Diagnostic and Statistical Manual of Mental Disorders