General 5 Flashcards

1
Q

where is dopamine MADE

A

substantia nigra

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2
Q

opsoclonus myoclonus cause and treatment

A

associated with infantile neuroblastoma; tx steroids or ACTH

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3
Q

Ramsay Hunt syndrome

A

herpetic neuritis of geniculate ganglion; affected nerves 7,8

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4
Q

most common CNS tumor in advanced AIDS

A

lymphoma

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5
Q

peak of neuronal PROLIFERATION

A

2nd trimester

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6
Q

peak of neuronal SYNAPTOGENESIS

A

toddler period (and doesn’t conclude until age 30!)

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7
Q

most frequent CNS opportunistic infxn in AIDS

A

toxoplasmosis

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8
Q

slowest of the prion diseases

A

Gerstmann-Straussler-Scheinker

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9
Q

Bell’s palsy most often due to

A

occult HSV

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10
Q

what does tetanus toxin do?

A

blocks GABA and glycine in spinal cord

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11
Q

Anton’s syndrome

A

pts deny blindness; due to b/l PCA involvement

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12
Q

Balint’s syndrome

A

due to basilar involvement (unlike Antons - PCA)

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13
Q

inhalant abuse can lead to

A

polyneuropathy (distal)

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14
Q

Meige’s syndrome

A

blepharospasm and oromandibular dystonia

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15
Q

scanning speech

A

cerebellum injury

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16
Q

aphemia

A

muteness with normal reading, writing, comprehension; due to involvement of Broca’s

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17
Q

opens NMDA receptor

A

glutamate AND glycine

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18
Q

best somatoform prognosis

A

conversion

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19
Q

only drug that is selective GABA reuptake inhibitor

A

tiagabine (gabitril)

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20
Q

GABA-A receptor is what kind of channel?

A

chloride

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21
Q

drug that is equal to BZDs for etoh w/d

A

carbamazepine

22
Q

sign of AVM

A

auscultating head and hearing bruit; sz also common

23
Q

cause of childhood dementia and Parkinsonism

A

Hallervorden-Spatz; iron in basal ganglia, cysteine dioxygenase

24
Q

how to treat lithium DI

A

amiloride with HCTZ

25
Q

mirtazapine MOA

A

blocks alpha2 presynaptic receptors

26
Q

fungus that causes PNA, invades vessels

A

Aspergillus

27
Q

funds that causes CNS abscess, liver dz, flu-like infection

A

histoplasma

28
Q

which gender more commonly has depression?

A

women

29
Q

cardiac effects of cannabis

A

tachycardia

30
Q

developed idea of transitional object

A

Winnicott

31
Q

paranoid-schizoid position

A

Klein: world split into good and bed elements

32
Q

BPRS used for which disorders?

A

schizophrenia and psychosis

33
Q

sleep terrors

A

… have amnesia for the event

34
Q

often associated with retrograde ejaculation

A

mellaril (thioridazine)

35
Q

NTs affected by MDMA

A

dopamine AND serotonin

36
Q

elevated ACE in CSF, neuropathies

A

sarcoidosis

37
Q

hypersomnia followed by psych sx

A

Kleine-Levin syndrome

38
Q

Alexia without agraphia

A

Left PCA: selenium of corpus callosum

39
Q

childhood disorder with precuts excavated, lens dislocation, Marfan’s habits, MR, scoliosis

A

Homocystinuria

40
Q

bupropion is a substrate of

A

2B6

41
Q

___% of striatal dopamine and mitral neurons lost before PD sx arise

A

60-85

42
Q

triptan MOA

A

agonists of 1B and 1D

43
Q

helps with chorea in HD

A

tetrabenazine

44
Q

stiff person syndrome associated with

A

diabetes, polyendocrinopathy, antibodies to glutamic acid decarboxylase

45
Q

anatomy of semantic memory

A

inferotemporal lobes

46
Q

anatomy of procedural memory

A

basal ganglia, cerebellum, SMA

47
Q

anatomy of episodic memory

A

medial temporal, anterior thalamic nuclei, mammillary bodies, fornix, prefrontal cortex

48
Q

NT involved with LSD

A

serotonin

49
Q

validity scales of MMPI

A

lie scale, infrequency scale, suppressor scale

50
Q

MMPI scale used to decrease false positives and false negatives

A

suppressor scale

51
Q

MMPI scale used to detect malingering

A

infrequency scale