General 5 Flashcards
where is dopamine MADE
substantia nigra
opsoclonus myoclonus cause and treatment
associated with infantile neuroblastoma; tx steroids or ACTH
Ramsay Hunt syndrome
herpetic neuritis of geniculate ganglion; affected nerves 7,8
most common CNS tumor in advanced AIDS
lymphoma
peak of neuronal PROLIFERATION
2nd trimester
peak of neuronal SYNAPTOGENESIS
toddler period (and doesn’t conclude until age 30!)
most frequent CNS opportunistic infxn in AIDS
toxoplasmosis
slowest of the prion diseases
Gerstmann-Straussler-Scheinker
Bell’s palsy most often due to
occult HSV
what does tetanus toxin do?
blocks GABA and glycine in spinal cord
Anton’s syndrome
pts deny blindness; due to b/l PCA involvement
Balint’s syndrome
due to basilar involvement (unlike Antons - PCA)
inhalant abuse can lead to
polyneuropathy (distal)
Meige’s syndrome
blepharospasm and oromandibular dystonia
scanning speech
cerebellum injury
aphemia
muteness with normal reading, writing, comprehension; due to involvement of Broca’s
opens NMDA receptor
glutamate AND glycine
best somatoform prognosis
conversion
only drug that is selective GABA reuptake inhibitor
tiagabine (gabitril)
GABA-A receptor is what kind of channel?
chloride
drug that is equal to BZDs for etoh w/d
carbamazepine
sign of AVM
auscultating head and hearing bruit; sz also common
cause of childhood dementia and Parkinsonism
Hallervorden-Spatz; iron in basal ganglia, cysteine dioxygenase
how to treat lithium DI
amiloride with HCTZ
mirtazapine MOA
blocks alpha2 presynaptic receptors
fungus that causes PNA, invades vessels
Aspergillus
funds that causes CNS abscess, liver dz, flu-like infection
histoplasma
which gender more commonly has depression?
women
cardiac effects of cannabis
tachycardia
developed idea of transitional object
Winnicott
paranoid-schizoid position
Klein: world split into good and bed elements
BPRS used for which disorders?
schizophrenia and psychosis
sleep terrors
… have amnesia for the event
often associated with retrograde ejaculation
mellaril (thioridazine)
NTs affected by MDMA
dopamine AND serotonin
elevated ACE in CSF, neuropathies
sarcoidosis
hypersomnia followed by psych sx
Kleine-Levin syndrome
Alexia without agraphia
Left PCA: selenium of corpus callosum
childhood disorder with precuts excavated, lens dislocation, Marfan’s habits, MR, scoliosis
Homocystinuria
bupropion is a substrate of
2B6
___% of striatal dopamine and mitral neurons lost before PD sx arise
60-85
triptan MOA
agonists of 1B and 1D
helps with chorea in HD
tetrabenazine
stiff person syndrome associated with
diabetes, polyendocrinopathy, antibodies to glutamic acid decarboxylase
anatomy of semantic memory
inferotemporal lobes
anatomy of procedural memory
basal ganglia, cerebellum, SMA
anatomy of episodic memory
medial temporal, anterior thalamic nuclei, mammillary bodies, fornix, prefrontal cortex
NT involved with LSD
serotonin
validity scales of MMPI
lie scale, infrequency scale, suppressor scale
MMPI scale used to decrease false positives and false negatives
suppressor scale
MMPI scale used to detect malingering
infrequency scale