Gene Regulation Question

Question 1

Draw components needed for transcription of a gene

Answer 1

Question 2

Draw a flow chart of the points in gene regulation

Answer 2

Question 3

Components of Transcription Factors

Answer 3

Question 4

An example of a transcription factor

Answer 4

Estrogen receptor, glucocorticoid receptor.

Bind to specific DNA sequences in response to steroid hormones and regulate target genes.

Question 5

What does the mediator complex do

Answer 5

20 subunits not required for transcription but transducer +/-ve signals from gene specific activators and repressirs

Regulates the CTD kinase activity of TFIIH

Role in tissue specific gene expression by binding to some factors and allowing certain genes to be active etc

Question 6

Effects of methylation/acetylation on histones

Answer 6

Question 7

Effects of methylation/acetylation on histones

Answer 7

Question 8

GH transcription factor

Answer 8

Pit-1

Question 9

Capping enzyme adds ___

Answer 9

7-methylguanosine

Modified guanine