Gene Regulation 1

Question 1

3 ways genes regulated in prokaryotes

Answer 1

Change substrate concentration, enzyme efficiency, and quantity of enzyme

Question 2

Why regulate gene expression

Answer 2

Prevent energy wastage and ensure only necessary proteins are made

Question 3

5 ways substrate availability is regulated

Answer 3

• Km
• metal ions and cofactors
• proximity of enzymes
• compartmentalizations
• macromolecule complexes

Question 4

Ways to regulate enzyme activity (regulate the number of enzymes or turn on/off)

Answer 4

-allosteric (feedback, reversible)
-covalent modification (proteolysis, irreversible.
Interconvertible (phospho, dephospho) reversible)