DNA Replication II Flashcards
1
Q
DNA Polymerase gamma exonuclease domain mutation
A
Cause increase in mtDNA mutations
2
Q
DNA polymerase game linker regions
A
A467T mutation are most common and lower protein activity
3
Q
DNA polymerase gamma polymerase domain mutation
A
Cause PEO
4
Q
Pol alpha
A
Contains primase
5
Q
Pol beta
A
Repair
6
Q
Pol gamma
A
Replicates mitochondrial DNA. 3-5 exonuclease activity
7
Q
Pol delta
A
Elongate Okazaki fragments of lagging strand. 3 to 5 exonuclease activity
8
Q
Pol epsilon
A
Elongate leading strand. 3 to 5 exonuclease activity
