Gene mutations

Question 1

gene mutation

Answer 1

change in the number, or sequence, of bases in a particular gene

Question 2

what are the factors that increase the chances of mutations called ?

Answer 2

mutagens

Question 3

what are the types of gene mutation ?

Answer 3

base deletion
base insertion
base substitution

Question 3

base deletion

Answer 3

one or more bases lost from the sequence

Question 4

base insertion

Answer 4

one or more bases added to the sequence

Question 5

base substitution

Answer 5

one or more bases changed for a different base

Question 6

point mutation

Answer 6

if a gene mutation involves only one base

Question 7

give an example of a point mutation

Answer 7

sickle cell anaemia

Question 8

sickle cell anaemia - what is it

Answer 8

a condition common among people originating from areas where malaria is endemic

Question 9

sickle cell anaemia

Answer 9

• in the gene that codes for part of haemoglobin
• base substitution - A replace T - causing valine instead of glutamic acid

Question 10

why does valine not have a positive charge ?

Answer 10

loss of ionic bonds and a change in tertiary structure

Question 11

what does abnormal haemoglobin lead to ?

Answer 11

a chance in the red blood cell shape and causes them to clump together