Gene expression Flashcards
5 stages of gene expression regulation
Repression, De-repression, Activation. Deactivation, Attenuation.
Repression
when a repressor protein blocks transcription of a gene. Binds to promoter region to stop transcription
De-repression
when a repressor protein is inactivated and no longer represses.
Activation
when an activator protein promotes faster transcription.
Deactivation
when the activator protein is inactivated and no longer promotes.
Attenuation
when the regulated protein stops being transcribed even in the absence of repression
Operons
is gene or series of genes that are bundled together on the same sequence of DNA and whose expression are under the control of at least one regulator protein.
Regulon
is a series of operons that are be scattered throughout the genome each of which is under the control of the same regulatory protein. Allows more and more complex regulatory controls over sub sets of the gene in global response