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Pharmaceutics 2 > Gels > Flashcards

Gels Flashcards

1
Q

Define the gels

A

It is a semi-solid dispersion system containing a gelling agent in sufficient quantities to impart a 3 dimensional polymeric matrix.

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2
Q

Gels containing a preservative such as …..

A

Methylparapen, propyleparaben

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3
Q

Gels may contain stabilizers such as…..

A

EDTA

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4
Q

What are the gelling agents ?

A

These are substances when added to an aqueous mixture increase its viscosity without modifying its other properties.

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5
Q

What are the importance of the gelling agents?

A

Providing body.
Increase stability.
Improve suspension of added ingreadients.

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6
Q

What are the types of gelling agents?

A 
1_ natural polymers:
*proteins
*polysaccharides
2_ semi-synthetic polymeres:
* celluse derivatives.
3_ synthetic polymers
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7
Q

Define the controlled release gel

A

A controlled released drug or preparation is released into the body in specified amount and over a period of time.
The controlled release syatem is designed to release the drug active ingredients gradually over time.

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8
Q

Define the Organogel.

A

Is a non crystalline, non glassy thermo reversible solid materials composed of liquid organic phase enterapped in a three dimantionally cross linked network.

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9
Q

Gels in which vehicles has been removed leaving a polymer network

A

Xerogel

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10
Q

Type of Gel have usually retain high porodity (15-50%)

A

Xerogel

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11
Q

Type of gel formulated from polymer with solvent like glycerin or poly ethylene glycol
Have no water

A

Non aqueous gel

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12
Q

Define the thermosensitive sol-gel revirsible hyrogel.

A

Aqurous polymer solution that are transformed into gels by changes in inviromental condition as PH and temp.

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13
Q

Define the Emulgel.and what is the importance of it ?

A

It is the formulation of emulsion and adding a gelling agent to convert the emulsion into gel.
The importance:
1This preparation is capable of holding hydrophilic as well as hydrophopic drugs.
2 the micro/nano emulsion allow faster and better absorption of the preparation.

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14
Q

Define the paste.

A

Semi solid preparation containing high conce. Of insoluble powdered substances(20%) dispersed in a sutible base.

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15
Q

Less grasy and moreabsorptive, stiffer in consistency than ointment

A

Paste

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16
Q

What are the characterstics of pastes?

A

1_Stiffer than other semisolid preparation, hence it is stable on the site of application.
2_Don’t interfer with non infected area.
3_Less greasy than ointment.
4_Used in case of lesions.

17
Q

What are the types of pastes?

A

1_Ointment-like.

2_Jelly pastes.

18
Q

How can we classifing the pastes?

A

1_Fatty pastes:
This formulation are consist of fatty or oleoginous bases.
2_Aqueous Gel Pastes:
This are prepared with water miscible bases.
3_Hydrocolloid Pastes:
This consist of hydrocarbon bases.

19
Q

Zinc oxide paste is an example on …..

A

Fatty pastes

20
Q

Sodium hydroxymethylcellus, and Titanium dioxide pastes are example on …..

A

Aqueous gel paste

21
Q

Tooth pastes, Oxide gelatin pastes are example on ……

A

Hydrocolloid pastes.

22
Q

Is indicated for aphthous alcer (Cancke sores)

A

Apsol

23
Q

Define the toothpastes.

A

Is a paste or gel dentifrice used to clean and improve the appearance of health of teeth.
Used to promote good oral hygiene and remove of dental plaque and food.

24
Q

What are the characters of tooth pastes?

A 
Free from gritty particles 
Good taste and flavour.
Stable.
Not dry upon standing.
Have suitable consistency.
25
Q

What are the Abrasive ?

A

Are solid dentifrice cleaning materials whose remove residual stains from teeth.

26
Q

What are the disadvantages of soap to be used as a detergents?

A

1_ effective only in alkaline PH.
2_ have high PH which is irritating the gums.
3_ incompatibility with saliva and hard water.
4_ incompatabil with some falvoring agents.
5_ incompatabil with some polishing agents.
6_have unpleasent taste.

27
Q

Sodium lauryl sulphate are an example …..

A

Newer detergents

28
Q

What are the main action of humactants?

A

To retain moisture when tha paste are exposed to air, thus preventing the paste from being dried.

29
Q

Glycerol, sorbitol, and propylene glycol are the most common …….

A

Humactant

30
Q

Binders are hydrophobic colloids (t or f)

A

F hydrophilic

Pharmaceutics 2 (10 decks)

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