ged 9 Flashcards
what is a silent mutation
doesn’t affect the encoded acid
what is a nonsense mutation
coden changed to a stop codon so we get truncated protein
what is a missense mutation
we get a different amino acid as codon has changed
wild type
functional protein normal
are LOF genes recessive or dominant
recessive
is GOF allele recessive or dominant
dominant
what is incomplete dominance
the heterozygote phenotype is intermediate between the two homozygote phenotypes
what is co dominance
heterozygotes show phenotype of both alleles eg blood groups
multiple alleles
may be more than two alleles for a single gene eg dominance series A> a^t>a
what is pleiotropy
when one gene may influence more than one trait eg lethal alleles control the colourof fur and the viability
what does lethality cause
skewed phenotypic ratios
achondroplasia is lof or gof
gof cuases premature replacement of cartilage with bone
lethal alleles tend to be
homozygous recessive