ged 14 Flashcards
nullisomy
missing a pair of homologous chromosomes
monosomy
loss of a single chromosome 2n-1
trisomy
one extra chromsome2n+1
tetrasomy
an extra pair of chromosomes 2n+2
how does non disjunction arise
abnormal segregation during meiosis
or failure in separation of sister chromatids
what does non disjunction result in
an aneuploid embryo (extra chromosome or a missing chromosome )
what is down syndrome an example of
trisomy 2n+1
wht is translocation
when one part of a chromosome becomes fused with a different chromosome
turner syndrome XO is an example of
monosomy 2n-1
karyotype 45, X
trisomy in sex chromsomes
Klinefelter XXY
triplo X XXX
XYY syndrome
what leads to aneuploidy in older women
premature loss of cohesion in prophase one that gives two univalent
what is found in mtDNA
components required for translation
structural genes involved for oxidative phosphorylation
cpDNA
structural genes involved in photosynthesis
wht is meant by uniparental
only one of the two parents contribute to the next gneration
what is heteroplasmy
oocyte contains two different types of mitochondria wild type and mutant