Gastrointestinal tract 4 Flashcards

1
Q
  1. Ileum (HE)
A
  • EPITHELIUM: columnar enterocytes
    • crypts of Lieberkühn
    • goblet cells
    • lymphocytes
  • LAMINA PROPRIA:
    • hihly vascular loose cellular CT
    • penetrates core of intestinal villi with arteriole + central lymphatic vessel + smooth muscle
    • fibroblasts, leukocytes, macrophages, mast cells, lymphocytes, plasma cells
  • MUSCULARIS MUCOSA: inner circular, outer longitudinal
  • SUBMUCOSA:
    • Meissner’s plexus
    • large ganglion cells
    • no glands
    • circular folds of Kerckring
  • MUSCULARIS EXTERNA: Auerbach’s plexus, inner circular + outer longitudinal smooth muscle
  • SEROSA: simple squamous mesothelial cells + CT
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2
Q

Paneth cell

A
  • in crypts of Lieberkühn
  • exocrine serous glandular cells
  • eosinophilic granulation
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3
Q
  1. Ileum -Peyer’s patches (HE)
A

Peyer’s patches:

  • 10-300 round lymphoid follicles
  • located in lamina propria and submucosa
  • situated in anti-mesenteric wall
  • dome areas devoid of villi and crypts of lieberkuhn ⇒ low columnar or cuboidal cells overlie their surface
  • no goblet cells
  • Microfold cella (M-cells)- epithelial cells making pockets⇒ T-cells and APC migrate into pockets
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4
Q
  1. Colon (HE)
A
  • no circular folds of Kerckring or intestinal villi
  • tenia on outside, haustra + semilunar folds
  • EPITHELIUM: columnar absorptive cells + goblet cells
  • LAMINA PROPRIA:
    • closely packet crypts of Lieberkühn
    • narrow lumens, lined by goblet cells, enterocytes, enteroendocrine cells, stem cells
    • CT separates tubular glands
  • MUSCULARIS MUCOSA: inner circularm outer longitudinal
  • SUBMUCOSA: devoid of glands
  • MUSCULARIS EXTERNA: inner circular, outer longitudinal + tenia coli
  • SEROSA: subserosal CT, fat-filled appendices epiploicae
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5
Q
  1. Vermiform appenxid (HE)
A
  • dense all round filtration of lymphatic tissue
  • lymphoid follicles in lamina propria and submucosa
  • EPITHELIUM: columnar enterocytes, goblet cells, M-cells
  • crypts of Lieberkühn- less closely + shorter
  • Paneth cells
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