Gastrointestinal - The Basics Flashcards
foregut
pharynx to duodenum
midgut
duodenum to transverse colon
hindgut
distal transverse colon to rectum
developmental defects of anterior abdominal wall due to failure of:
- rostral fold closure: sternal defects
- lateral fold closure: omphalocele, gastroschisis
- caudal fold closure: bladder exstrophy
duodenal atresia
failure to recanalize (trisomy 21)
jejunal, ileal, colonic atresia
due to vascular accident (apple peel atresia)
midgut development
6th week - midgut herniates through umbilical ring
10th week - returns to abdominal cavity + rotates around SMA
gastroschisis
extrusion of abdominal contents through abdominal folds; not covered by peritoneum
omphalocele
persistence of herniation of abdominal contents into umbilical cord, covered by peritoneum
most common transesophageal anomaly
esophageal atresia with distral transesophageal fistula
EA + TEF
congenital pyloric stenosis
hypertrophy of pylorus causes obstruction
“olive” mass in epigastric region, nonbilious projectile vomiting ~ 2 wks.
firstborn males
annular pancreas
ventral pancreatic bud abnormally encircled 2nd part of duodenum; forms a ring of pancreatic tissue that may cause duodenal narrowing
pancreas divisum
ventral and dorsal parts fail to fuse at 8 weeks
retroperitoneal structures
SAD PUCKER Suprarenal/adrenal gland Aorta and IVC Duodenum (2nd, 3rd parts) Pancreas (except tail) Ureters Colon (descending and ascending) Kidneys Esophagus (lower 2/3) Rectum (lower 2/3)
falciform ligament connects
liver to anterior abdominal wall
falciform ligament contains
ligamentum teres hepatis (derivative of fetal umbilical vein)
falciform ligament fun fact
derivative of ventral mesentery
hepatoduodenal ligament connects
liver to duodenum
hepatoduodenal ligament contains
portal triad
hepatic artery
portal vein
common bile duct
hepatoduodenal ligament fun facts
Pringle maneuver - control bleeding
connects greater and lesser sacs
gastrohepatic ligament connects
liver to lesser curvature of stomach
gastrohepatic ligament contains
gastric arteries
gastrohepatic ligament fun facts
separates greater and lesser sacs on the right
may be cut during surgery to access lesser sac
gastrocolic ligament connects
greater curvature and transverse colon
gastrocolic ligament contains
gastroepiploic arteries
gastrocolic ligament fun fact
part of greater omentum
gastrosplenic ligament connects
greater curvature and spleen
gastrosplenic ligament contains
short gastrics, left gastroepiploic vessels
gastrosplenic ligament fun fact
separates greater and lesser sacs on the left
splenorenal ligament connects
spleen to posterior abdominal wall
splenorenal ligament contains
splenic artery and vein, tail of pancreas
Gut wall layers - inside to outside
MSMS
Mucosa - epithelium, lamina propria, muscularis mucosa
Submucosa - submucosal nerve plexus/Meissner’s
Muscularis externa - myenteric/Auerbach’s
Serosa (intraperitoneal)/Adventitia (retroperitoneal)
Slow wave frequency
Stomach
Duodenum
Ileum
Stomach - 3 waves/min
Duodenum - 12 waves/min
Ileum - 8-9 waves/min
esophagus histology
nonkeritanized stratified squamous epithelium
stomach histology
gastric glands
duodenum histology
villi, microvilli increase absorptive surface
Brunner’s glands (submucosa)
crypts of Lieberkuhn
jejunum histology
plicae circulares, crypts of Lieberkuhn
ileum histology
Peyer’s patches (lamina propria, submucosa)
plicase circulares (proximal ileum)
crypts of Lieberkuhn
largest number of goblet cells
colon histology
crypts
no villi
numerous goblet cells
Superior mesenteric artery syndrome
transverse portion (3rd segment) of duodenum is entrapped between SMA and aorta, causing intestinal obstruction
celiac trunk level
T12
SMA level
L1
left renal artery level
L1
inferior mesenteric artery level
L3
bifurcation of abdominal aorta level
L4
foregut blood supply
celiac artery
foregut parasym innervation
vagus
foregut structures supplied
stomach to proximal duodenum liver gallbladder pancreas spleen (mesoderm)
midgut blood supply
SMA
midgut parasym innervation
vagus
midgut structures supplied
distal duodenum to proximal 2/3 transverse colon
hindgut blood supply
IMA
hindgut parasym innervation
pelvic
hindgut structures supplied
distal 1/3 transverse colon to upper portion of rectum; splenic flexure is a watershed region
celiac trunk branches - think main blood supply of stomach
common hepatic
splenic
left gastric
strong anastomoses of celiac trunk
left and right gastroepiploics
left and right gastrics
blocked abdominal aorta branches - anastomotic compensation for arteries
superior epigastric + inferior epigastric
superior pancreaticoduodenal + inferior pancreaticoduodenal
middle colic + left colic
superior rectal + middle and inferior rectal
portosystemic anastomoses - think portal HTN
esophagus - esophageal varices
umbilicus - caput medusa
rectum - internal hemorrhoids
esophageal varices anastomosis
left gastric (portal) + esophageal (systemic)
caput medusa anastomoses
paraumbilical (portal) + superficial & inferior epigastric below umbilicus, superior epigastric & lateral thoracic above umbilicus (systemic)
internal hemorrhoids anastomoses
superior rectal (portal) + middle & inferior rectal (systemic)
portal HTN Tx
TIPS - transjugular intrahepatic portosystemic shunt
btwn portal & hepatic vv., shunt to systemic
internal hemorrhoids
painless, above pectinate line
venous drainage: superior rectral vein to inferior mesenteric vein to portal system
external hemorrhoids
painful, below pectinate line
venous drainage: inferior rectal vein to internal pudendal vein to internal iliac vein to IVC
The Liver
Zone I: periportal zone
affected 1st by vital hepatitis
The Liver
Zone II: intermediate zone
just a thing
The Liver
Zone III: pericentral vein/ centrilobular zone
affected 1st by ischemia
contains P450 system
most sensitive to toxic injury
site of EtOH hepatitis
The Liver
Blood flow
Zone I to III
The Liver
Bile flow
Zone III to I
femoral region contents lateral to medial
NAVEL
Nerve, Artery, Vein, Empty space, Lymphatics
femoral sheath contains all but nerve
diaphragmatic hernia
abdominal structures enter the thorax
hiatal hernia most common - stomach herniates upward through esophageal hiatus of diaphragm
indirect inguinal hernia
through the internal (deep) inguinal ring, external (superficial) inguinal ring, into scrotum
male infants - descent of testes
lateral to inferior epigastric artery
direct inguinal hernia
protrudes through inguinal (Hesselbach’s) triangle
medial to inferior epigastric artery
through external (superficial) inguinal ring only
older men
femoral hernia
protrudes below inguinal ligament through femoral canal below and lateral to pubic tubercle
more common in women
Hesselbach’s triangle borders
inferior epigastric vessels
laterial border rectus abdominis
inguinal ligament