Gastrointestinal Pharmacology Flashcards

1
Q

4 characteristics of GI disorders

A

Structural
Malabsorptive
Inflammatory
Neoplastic in nature

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2
Q

What is one of the most common GI disorders?

A

GERD

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3
Q

Which is the most effective available proton pump inhibitor?

A

Esomeprazole

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4
Q

True or false: Esomeprazole is the R enantiomer of omeprazole, which is formulated as a racemic mixture of R and S enantiomers

A

False. Esomeprazole is the S enantiomer of omeprazole

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5
Q

Adverse effects of PPIs

A

HA, nausea, disturbed bowel function, and abdominal pain

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6
Q

Two classes of agents that reduce acid production

A

PPIs and H2 receptor antagonists

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7
Q

What class of drugs neutralizes acid?

A

Antacids

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8
Q
Which of the following is not a compound commonly found in antacids?
Aluminum hydroxide 
Magnesium hydroxide
Sodium bicarbonate
Calcium bicarbonate
A

Calcium bicarbonate; however, calcium carbonate is commonly used in antacids

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9
Q

What two classes of drug promote mucosal defense?

A

Coating agents and prostaglandins

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