Gastrointestinal Pharmacology Flashcards
4 characteristics of GI disorders
Structural
Malabsorptive
Inflammatory
Neoplastic in nature
What is one of the most common GI disorders?
GERD
Which is the most effective available proton pump inhibitor?
Esomeprazole
True or false: Esomeprazole is the R enantiomer of omeprazole, which is formulated as a racemic mixture of R and S enantiomers
False. Esomeprazole is the S enantiomer of omeprazole
Adverse effects of PPIs
HA, nausea, disturbed bowel function, and abdominal pain
Two classes of agents that reduce acid production
PPIs and H2 receptor antagonists
What class of drugs neutralizes acid?
Antacids
Which of the following is not a compound commonly found in antacids? Aluminum hydroxide Magnesium hydroxide Sodium bicarbonate Calcium bicarbonate
Calcium bicarbonate; however, calcium carbonate is commonly used in antacids
What two classes of drug promote mucosal defense?
Coating agents and prostaglandins