Gastrointestinal Infections & Diarrhea Flashcards
Guest lecturer Shaw & Wold
Define diarrhea
3 or more loose or watery stools within 24 hours
Define the 4 different types of diarrhea
Define gastroenteritis
infection related to the stomach and small intestine
Define infectious colitis
infection located in the colon
Describe the etiology of infectious diarrhea
Describe the presentation of small bowel infectious diarrhea
Describe the presentation of large bowel infectious diarrhea
Describe the diagnosis of acute infectious diarrhea
Which organisms are difficult to grow on culture for stool samples/diarrhea testing
Vibrio & listeria - do GI panel instead
Describe the etiology & presentation of norovirus diarrhea
Describe the etiology & presentation of clostridium perfringens diarrhea
Describe the etiology & presentation of enterotoxigenic coli (E. Coli) diarrhea
Describe the etiology & presentation of vibrio cholerae diarrhea
Describe the etiology & presentation of listeria monocytogenes
Describe the etiology & presentation of aeromonas & plesiomonas diarhea
Describe the etiology & presentation of staph aureus diarrhea
Describe the etiology & presentation of salmonella diarrhea
Describe the etiology & presentation of campylobacter diarrhea
Describe the etiology & presentation of shigella
Describe the etiology & presentation of enterohemmorrhagic E coli
Describe the etiology & presentation of yersinia enterocolitica
Describe the etiology & presentation of c. diff
Describe the etiology & presentation of CMV/HSV diarrhea
Describe the etiology & presentation of botulism
Describe the etiology & presentation of ciguatera fish poisoning
Describe the etiology & presentation of scombroid
Describe the etiology & presentation of typhoid
Describe the etiology of intestinal parasites
Describe the etiology & presentation of brucella
Describe the etiology & presentation of ascaris
Describe the etiology & presentation of whipworm
Describe the etiology & presentation of pinworm
Describe the etiology & presentation of schistosomiasis
Describe the etiology & presentation of strongyloides
Describe the etiology & presentation of entamoeba histolytica
Describe the etiology & presentation of giardia
Describe the etiology & presentation of cryptosporidium
Describe the etiology of Rotavirus
Describe the presentation of rotavirus
Describe the treatment for rotavirus
What abx are implicated with C. diff
Describe the etiology of acute diarrhea
- <14 days
- mostly caused by infectious bug
- fever, vomiting, abd pain
Describe the etiology of chronic diarrhea
- > 30 days
- usually non-infectious
- warrants further eval to exclude malabsorptive disease
Describe the characteristics of small bowel diarrhea
- watery
- large volume
- associated with abd craming, bloating, gas, weight loss
- fever not likely
- occult blood not likely
- less inflammatory cells
- enteric viruses MC
Describe the characteristics of large bowel diarrhea
- inflammatory
- frequent, regular, small volume, often painful
- fever
- bloody/mucoid
- inflammatory cells present
- bacterial pathogens MC
What are the most common viral pathogens causing acute diarrhea
Norovirus, rotavirus, adenovirus, astrovirus, etc.
What bacteria commonly cause acute diarrhea
salmonella, campylobacter, shigella, enterotoxigenic E coli, C diff, etc.
What protozoa commonly cause acute diarrhea
cryptosporidium, giardia, cyclospora, entamoeba, etc.
Describe food poisoning
Diarrhea within 6hrs of eating
- generally staph aureus or bacillus cereus
- vomiting is a major symptom
Within 8-16 hrs = clostridium perfringens
Greater than 16 hrs = viral or other bacterial etiologies that require time for toxin to develop (ETAC)
When to do stool testing
- severe illness: hosp, hypovolemic, 6+ days of severe symptoms
- concern for inflammatory diarrhea: bloody, fever
- high risk host features: 70+ years old, immunocompromised, IBD, pregnant
- public health concern: food worker, healthcare worker, day care
- symptoms +1 week
Describe fecal leuk testing
- looking for WBC in stool
- WBC not normally there
- indicate infection with microorganisms that invade tissue or produce toxins that damage tissue
- can also be seen in IBD
- not accurate for inflammatory diarrhea
What is the danger zone for bacterial multiplication in food
40 degrees to 140 degrees F
List some infection control & prevention measures relevant to diarrhea
- avoid daycares, schools, water activities until no symptoms for at least 48 hrs
- avoid anal receptive and oral-anal sex until no symptoms for at least 48 hrs
- hand hygiene
- water purification tools
What diarrheal illness commonly causes guillain-barre syndrome
campylobacter (30-40% of GBS cases attributed)
90% of hemolytic uremic syndrome in kids is caused by which two diarrheal illnesses
E coli most common, then shigella