Gastrointestinal Drugs

Question 1

What is Aluminium hydroxide? Name its drug class, indication, and mechanism of action.

Answer 1

Aluminium hydroxide is an antacid used for indigestion. Its mechanism of action is neutralisation of gastric acid.

Aluminium hydroxide is commonly found in over-the-counter antacids.

Question 2

What is Magnesium hydroxide? Name its drug class, indication, and mechanism of action.

Answer 2

Magnesium hydroxide is an antacid used for indigestion. Its mechanism of action is neutralisation of gastric acid.

Magnesium hydroxide can also have a laxative effect.

Question 3

What is Ranitidine? Name its drug class, indication, and mechanism of action.

Answer 3

Ranitidine is a histamine H2 blocker used for indigestion and peptic ulcer. Its mechanism of action is blocks H2 receptors inhibiting gastric acid production in parietal cells.

Ranitidine was commonly used but has been withdrawn in many markets due to safety concerns.

Question 4

What is Omeprazole? Name its drug class, indication, and mechanism of action.

Answer 4

Omeprazole is a proton pump inhibitor used for indigestion and peptic ulcer. Its mechanism of action is blocks extrusion of H+ through proton pump in parietal cells.

Omeprazole is often prescribed for gastroesophageal reflux disease (GERD).

Question 5

What is Sucralfate? Name its drug class, indication, and mechanism of action.

Answer 5

Sucralfate is a mucosal strengthener used for peptic ulcer. Its mechanism of action is forms insoluble raft on ulcerated tissue protecting tissue and reducing pain.

Sucralfate requires an acidic environment for activation.

Question 6

What is Bismuth chelate? Name its drug class, indication, and mechanism of action.

Answer 6

Bismuth chelate is a mucosal strengthener used for peptic ulcer. Its mechanism of action is forms insoluble raft on ulcerated tissue protecting tissue and reducing pain.

Bismuth compounds are also effective against H. pylori.

Question 7

What is Amoxicillin? Name its drug class, indication, and mechanism of action.

Answer 7

Amoxicillin is a penicillin antibiotic used for peptic ulcer. Its mechanism of action is used in multi-therapy approach to eradicate H. pylori infections associated with peptic ulcers.

Amoxicillin is often combined with proton pump inhibitors for effective treatment.