Blood Disorders Flashcards
What is Abciximab? Name its drug class, indication, and mechanism of action.
Abciximab is a platelet inhibitor used for thrombosis. Its mechanism of action is mAB that binds to GPIIb/IIIa receptor and inhibits platelet aggregation.
What is Aspirin? Name its drug class, indication, and mechanism of action.
Aspirin is a NSAID platelet inhibitor used for thrombosis. Its mechanism of action is inhibits COX in platelets blocking production of aggregating agent TxA2.
What is Clopidogrel? Name its drug class, indication, and mechanism of action.
Clopidogrel is a platelet inhibitor used for thrombosis. Its mechanism of action is inhibits ADP-mediated platelet aggregation via GPIIb/IIIa receptor complex.
What is Heparin? Name its drug class, indication, and mechanism of action.
Heparin is an anticoagulant used for thrombosis. Its mechanism of action is bind to ATIII, inactivating thrombin and blocking clot formation.
What is Warfarin? Name its drug class, indication, and mechanism of action.
Warfarin is an anticoagulant used for thrombosis. Its mechanism of action is inhibits synthesis of vit K dependent coagulation factors.
What is Streptokinase? Name its drug class, indication, and mechanism of action.
Streptokinase is a thrombolytic used for thrombosis. Its mechanism of action is promotes conversion of plasminogen to plasmin.
What is Alteplase? Name its drug class, indication, and mechanism of action.
Alteplase is a thrombolytic (tPA) used for thrombosis. Its mechanism of action is promotes conversion of plasminogen to plasmin.
What is Factor VIII? Name its drug class, indication, and mechanism of action.
Factor VIII is a clotting factor used for bleeding disorders. Its mechanism of action is replaces missing clotting factor VIII in haemophilia A.
What is Factor IX? Name its drug class, indication, and mechanism of action.
Factor IX is a clotting factor used for bleeding disorders. Its mechanism of action is replaces missing clotting factor IX in haemophilia B.
What is Vitamin K1? Name its drug class, indication, and mechanism of action.
Vitamin K1 is a vitamin used for bleeding disorders. Its mechanism of action is promotes formation of clotting factors II, IX and X.
What is Desmopressin? Name its drug class, indication, and mechanism of action.
Desmopressin is an ADH used for bleeding disorders. Its mechanism of action is increases von Willebrand’s factor coagulation activity.