Blood Disorders Flashcards

1
Q

What is Abciximab? Name its drug class, indication, and mechanism of action.

A

Abciximab is a platelet inhibitor used for thrombosis. Its mechanism of action is mAB that binds to GPIIb/IIIa receptor and inhibits platelet aggregation.

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2
Q

What is Aspirin? Name its drug class, indication, and mechanism of action.

A

Aspirin is a NSAID platelet inhibitor used for thrombosis. Its mechanism of action is inhibits COX in platelets blocking production of aggregating agent TxA2.

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3
Q

What is Clopidogrel? Name its drug class, indication, and mechanism of action.

A

Clopidogrel is a platelet inhibitor used for thrombosis. Its mechanism of action is inhibits ADP-mediated platelet aggregation via GPIIb/IIIa receptor complex.

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4
Q

What is Heparin? Name its drug class, indication, and mechanism of action.

A

Heparin is an anticoagulant used for thrombosis. Its mechanism of action is bind to ATIII, inactivating thrombin and blocking clot formation.

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5
Q

What is Warfarin? Name its drug class, indication, and mechanism of action.

A

Warfarin is an anticoagulant used for thrombosis. Its mechanism of action is inhibits synthesis of vit K dependent coagulation factors.

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6
Q

What is Streptokinase? Name its drug class, indication, and mechanism of action.

A

Streptokinase is a thrombolytic used for thrombosis. Its mechanism of action is promotes conversion of plasminogen to plasmin.

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7
Q

What is Alteplase? Name its drug class, indication, and mechanism of action.

A

Alteplase is a thrombolytic (tPA) used for thrombosis. Its mechanism of action is promotes conversion of plasminogen to plasmin.

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8
Q

What is Factor VIII? Name its drug class, indication, and mechanism of action.

A

Factor VIII is a clotting factor used for bleeding disorders. Its mechanism of action is replaces missing clotting factor VIII in haemophilia A.

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9
Q

What is Factor IX? Name its drug class, indication, and mechanism of action.

A

Factor IX is a clotting factor used for bleeding disorders. Its mechanism of action is replaces missing clotting factor IX in haemophilia B.

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10
Q

What is Vitamin K1? Name its drug class, indication, and mechanism of action.

A

Vitamin K1 is a vitamin used for bleeding disorders. Its mechanism of action is promotes formation of clotting factors II, IX and X.

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11
Q

What is Desmopressin? Name its drug class, indication, and mechanism of action.

A

Desmopressin is an ADH used for bleeding disorders. Its mechanism of action is increases von Willebrand’s factor coagulation activity.

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