CNS drugs Flashcards
What is Levodopa? Name its drug class, indication, and mechanism of action.
Levodopa is a dopamine precursor used for Parkinsonism. Its mechanism of action is converted to dopamine to boost lowered dopamine levels.
What is Carbidopa? Name its drug class, indication, and mechanism of action.
Carbidopa is a dopa decarboxylase inhibitor used for Parkinsonism. Its mechanism of action is inhibits peripheral metabolism of levodopa by decarboxylase.
What is Bromocriptine? Name its drug class, indication, and mechanism of action.
Bromocriptine is a dopamine D2 receptor agonist used for Parkinsonism. Its mechanism of action is replaces depleted dopamine.
What is Benztropine? Name its drug class, indication, and mechanism of action.
Benztropine is a muscarinic M1 Ach receptor blocker used for Parkinsonism. Its mechanism of action is blocks excessive parasympathetic activation of fine motor neurones in striatum.
What is Donepezil? Name its drug class, indication, and mechanism of action.
Donepezil is an acetylcholinesterase inhibitor used for Alzheimer’s. Its mechanism of action is improve cholinergic function in remaining cortical neurons.
What is Riluzole? Name its drug class, indication, and mechanism of action.
Riluzole is a glutamate release inhibitor used for ALS. Its mechanism of action is inhibitor of glutamate neurotransmission and accumulation, reducing neuronal death.
What is Baclofen? Name its drug class, indication, and mechanism of action.
Baclofen is a GABAB receptor blocker used for ALS. Its mechanism of action is relief of ALS-associated spasticity.
What is Diazepam? Name its drug class, indication, and mechanism of action.
Diazepam is a benzodiazepine used for anxiety. Its mechanism of action is potentiates the inhibitory effect of GABA in CNS neurons.
What is Flumazenil? Name its drug class, indication, and mechanism of action.
Flumazenil is a BZP antagonist used for BZP overdose. Its mechanism of action is blocks the sedating effects of BZPs in overdose.
What is Phenobarbital? Name its drug class, indication, and mechanism of action.
Phenobarbital is a barbiturate used to control seizure or for anxiety/sedation. Its mechanism of action is potentiates the inhibitory effect of GABA in CNS neurons.
What is Zolpidem? Name its drug class, indication, and mechanism of action.
Zolpidem is a “Z” drug used for sedation and sleep disorders. Its mechanism of action is potentiates the inhibitory effect of GABA in CNS neurons.
What is Fluoxetine? Name its drug class, indication, and mechanism of action.
Fluoxetine is an SSRI antidepressant used for depressive disorders. Its mechanism of action is block reuptake of serotonin resulting in elevation of synaptic levels.
What is Venlafaxine? Name its drug class, indication, and mechanism of action.
Venlafaxine is an SNRI antidepressant used for depressive disorders. Its mechanism of action is block reuptake of serotonin and noradrenaline resulting in elevation of synaptic levels.
What is Duloxetine? Name its drug class, indication, and mechanism of action.
Duloxetine is an SNRI antidepressant used for depressive disorders. Its mechanism of action is block reuptake of serotonin and noradrenaline resulting in elevation of synaptic levels.
What is Imipramine? Name its drug class, indication, and mechanism of action.
Imipramine is a TCA antidepressant used for depressive disorders. Its mechanism of action is block reuptake of serotonin and noradrenaline resulting in elevation of synaptic levels.
What is Phenelzine? Name its drug class, indication, and mechanism of action.
Phenelzine is a monoamine oxidase inhibitor used for depressive disorders. Its mechanism of action is inhibition of MAO resulting in increased stores of NA, serotonin and dopamine in the neuron.
