Gastrointestinal Drugs Flashcards
What is the mechanism of action of Gaviscon?
When would you prescribe it?
Gaviscon inhibits the proteolytic pepsin enzyme which neutralises stomach acid.
It is prescribed to treat heartburn and indigestion.
What is the mechanism of action of Loperamide?
When would you prescribe it?
Loperamide binds to the opiate receptor in the gut wall and slows the passage of food through the gut.
Loperamide is used to treat sudden or recurrent diarrhoea.
What is the mechanism of action of Lansoprazole?
When would you prescribe it?
Lansoprazole is a proton pump inhibitor. It inhibits gastric hydrogen/potassium adenosine triphosphatase, blocking the secretion of gastric acids.
Lansoprazole is used to treat gastro-oesophageal reflux. It is also used in the treatment or prevention of peptic ulcers.
What is the mechanism of action of Omeprazole?
When would you prescribe it?
Omeprazole is a proton pump inhibitor. It irreversibly inhibits the hydrogen/potassium adenosine triphosphatase, inhibiting the secretion of gastric acid.
Omeprazole is used to treat stomach/duodenal ulcers and reflux oesophagitis.
What is the mechanism of action of Ranitidine?
When would you prescribe it?
Ranitidine reversibly binds to histamine receptors, which reduces the secretion of gastric acid.
Ranitidine is used to help stomach ulcers to heal, as it reduces acid production for 4-8 weeks.
What drug classification does the components of Gaviscon belong to?
Antacids
What drug classification does Loperamide belong to?
Antidiarrhoeal - opioid receptor agonists
What drug classification does Lansoprazole and Omeprazole belong to?
Proton Pump Inhibitors
What drug classification does Ranitidine belong to?
Histamine H2 Antagonist
