Drugs for Infections

Question 1

What is the mechanism of action of Clarithromycin?

Answer 1

Clarithromycin binds to subunit 50S of the bacterial ribosome and inhibits bacterial protein synthesis. This works to stop the growth of bacteria.

Question 2

What is the mechanism of action of Erythromycin?

Answer 2

Erythromycin binds to the 23S ribosomal RNA molecule in the 50S subunit of ribosomes in bacterial organisms. This inhibits protein synthesis and kills or prevents growth of the bacteria as a result.

Question 3

What is the mechanism of action of Amoxicillin?

Answer 3

Amoxicillin binds to one or more penicillin binding proteins (PBPs). This inhibits bacterial cell wall synthesis, stopping the growth of bacteria.

Question 4

What is the mechanism of action of Benzylpenicillin?

Answer 4

Benzylpenicillin weakens bacterial cells walls by inhibiting bacterial wall synthesis. It does this through the inhibition of DD-transpeptidase.

Question 5

What is the mechanism of action of Clotrimazole?

Answer 5

Clotrimazole inhibits biosynthesis of ergosterol which damages the permeability barrier of fungal cell walls. The contents of these cells then leak out and the fungus will die.

Question 6

What drug classification does Clarithromycin and Erythromycin belong to?

Answer 6

Macrolide Antibiotics

Question 7

What drug classification does Amoxicillin and Benzylpenicillin belong to?

Answer 7

Penicillin Antibiotics

Question 8

What class of drug does Clotrimazole, Econazole, Miconazole and Fluconazole belong to?

Answer 8

Antifungals

Question 9

When would Clotrimazole be prescribed?

Answer 9

Clotrimazole is used to treat fungal infections, such as thrush of the ear, mouth, penis or vagina.

Question 10

When would Benzylpenicillin be prescribed?

Answer 10

Benzylpenicillin is used to treat wound infections as well as ear, nose, throat and respiratory infections.

Question 11

When would Amoxicillin be prescribed?

Answer 11

Amoxicillin is used to treat ear, nose, throat and respiratory infections.

Question 12

When would Erythromycin be prescribed?

Answer 12

Erythromycin is used to treat patients that suffer from migraine attacks or cluster headaches.

Question 13

When would Clarithromycin be prescribed?

Answer 13

Clarithromycin is prescribed for the treatment of ear, nose, throat and respiratory infections.