GASTROINTESTINAL DRUGS Flashcards

1
Q

Prevent expulsion of stomach contents by decreasing stimulation of either the chemoreceptor trigger zone, near the medulla, or the vomiting center in the medulla

PREVENTS?

A

ANTI-EMETICS; Nausea/Vomiting

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2
Q

Dramamine
Phenergan

A

Antihistamines

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3
Q

Scopolamine

A

Anticholinergic

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4
Q

Thorazine

A

Phenothiazines

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4
Q

Granisetron Ondansetron

A

Serotonin receptor antagonist

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5
Q

non-pharmacologic measures for nausea/vomiting

A

Dry toast, Tea, Crackers

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6
Q

Store anti-emetics drug in____ & _____ container.

A

tight, light resistant

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7
Q

Neutralize gastric acid

A

ANTACIDS

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8
Q

Aluminum hydroxide,
Magnesium hydroxine
AlOH + MgOH (Maalox/Magaldrate)

are used for?

A

Peptic ulcers, reflux esophagitis, hiatal hernia

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9
Q

Adverse reaction of aluminum compounds

A

Constipation

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10
Q

Adverse reaction of Magnesium compounds

A

DIARRHEA

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11
Q

ANTACIDS are administered with?

A

8 oz of glass water

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12
Q

Recommended diet high in?

A

Calcium, Iron

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13
Q

Inhibit secretion of pepsin
Block release of histamines

A

ANTI-PEPTIC ULCER DISEASE

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14
Q

4 types of ANTI-PEPTIC ULCER DISEASE

A
  1. Proton-pump Inhibitor (PPI)
  2. H2-receptor Blockers
  3. Cytoprotective agent
  4. Anti-cholinergics
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15
Q

Omeprazole
Lansoprazole

A

Proton-pump Inhibitor (PPI)

16
Q

Cimetidine
Ranitidine
Famotidine

A

H2-receptor Blockers

17
Q

Sucralfate
Misoprostol

A

Cytoprotective agent

18
Q

Chlordiazepoxide
Atropine sulfate

A

Anti-cholinergics

19
Q

Anti-peptic ulcer disease is used for management of

A

peptic ulcer disease, GERD; protects gastric mucosa from hydrochloric acid production

20
Q

Anti-peptic ulcer disease is given on

A

EMPTY STOMACH

21
Q

Avoid____ within 30 minutes of sucralfate

A

Antacids

22
Q

Avoid antacids within ____ hours of other anti-ulcer drugs

A

1-2

23
Q

Administer other drugs one to two hours after ____

A

Sucralfate

24
Q

MUST AVOID when taking ati-peptic ulcer disease

A

alcohol, spicy food and caffeinated beverages.

25
Q

full effect takes

A

2 weeks

26
Q

Forms the stool; Tx for diarrhea

A

ANTI-DIARRHEAL

27
Q

Kaolin and Pectin

A

Fluid absorbents (Decrease fluid content)

28
Q

Diphenoxylate hydrochloride
Loperamide hydrochloride

A

Motility Suppressants (Decrease GI motility)

29
Q

Lactobacillus acidophilus

A

Enteric bacterium replacements

30
Q

CI for anti-diarrheal

A

Ulcerative colitis

31
Q

Motility suppressants may cause

A

physical dependence

32
Q

Agents which facilitate defecation, and treat constipation
+ Increase bulk within the bowel
+ Lubricate the intestinal walls
+ Increase peristalsis

A

LAXATIVES

33
Q

Mineral oil
Colace
Metamucil
Dulcolax
Milk of magnesia

TREATS?

A

Constipation

34
Q

Intestinal lubricants inhibit absorption of

A

fat soluble vitamins

35
Q

fat soluble vitamins like ____ (excrete excessive loss of water) which may cause

A

Saline cathartics; dehydration, hypernatremia

36
Q

To treat constipation, diet must include

A

High fiber, fluid intake