CARDIO DRUGS Flashcards
Make heart beat slower but stronger
+ Improve pumping ability of heart
+ Increase force of heart’s contraction
+ Decrease rate of contraction
+ Increases cardiac output
CARDIAC GLYCOSIDES
Digoxin
Digitoxin
USED FOR?
Congestive Heart Failure
Atrial flutter, Atrial fibrillation
CI FOR CARDIAC GLYCOSIDES
Ventricular tachycardia
Ventricular fibrillation
Second and third degree heart block
Vision changes in client w too much digoxin
yellow-green halos
Before giving glycosides, check apical pulse and heart rhythm. Report if
<60 bpm (adult)
<90 bpm (infants)
Therapeutic range of DIGOZXIN
0.5 to 2.0 mg/mL
Antidote for Digoxin tocicity
DIGOXIN IMMUNE FAB (Digibind)
Daily weights: Report increase of?
2 pounds
Dilate peripheral blood vessels
+ Prevent hypertension
ANTI-HYPERTENSIVES
Captopril
Enalapril
Angiotensin-converting Enzyme Inhibitors (ACE-I)
Losartan
Telmisartan
Irbesartan
Angiotensin II Receptor Blockers (ARBs)
Verapamil
Diltiazem
Nifedipine
Nicardipine
Calcium Channel Blockers (CCB)
Hydralazine hydrochloride
Reserpine
Prazosin hydrochloride
Methyldopa
Clonidine
OTHERS
Encourage intake of foods high in
Vitamin B
___ is able to break down clots
Plasmin
Binds with plasminogen to dissolve thrombi (clots) in coronary arteries
THROMBOLYTICS
Streptokinase
Urokinase
THROMBOLYTICS
THROMBOLYTICS used for
MI, DVT, Pulmonary emboli
3 things to monitor of thrombolytics administration
bleeding times, coagulation studies, allergic reactions
Antidote for thrombolytics
Aminocaproic acid
Lower LDL levels by reducing the synthesis of cholesterol and/or triglycerides
ANTI-LIPIDEMIC
Atorvastatin
Simvastatin
HMG-CoA Reductase Inhibitors
Colestipol
Cholestyramine
Bile Acid Sequestrants
2 things to monitor on anti-lipidemic administration
cholesterol levels,
liver function test
____ and ____ will be necessary during treatment
blood work + eye exams
Recommended diet for hypercholesterolemia
low cholesterol; high-fiber
Dilate arterioles which lowers peripheral vascular resistance (afterload)
ANTI-ANGINALS
Nitroglycerin
Isosorbide dinitrate
Isosorbide mononitrate
used for?
ANGINA
Sublingual Medications
MUST:
1.
2.
Offer sips of water before giving. (dryness may inhibit absorption)
Instruct to put under the tongue and leave until fully dissolved
Translingual Medications (tongue spray)
MUST:
1.
2.
Instruct the client to spray directly against the oral mucosa.
Avoid inhaling the spray.
Transmucosal-Buccal Medications
MUST:
1.
Instruct the client to put between the upper lip and gum or in the buccal area between the cheek and
gum.
Transdermal Patch
MUST:
1.
2.
Instruct the client to apply the patch over a hairless area, using a new patch and a different site each day.
Instruct the client to remove the patch after 12-14 hours, allowing 10-12 “patch-free” hours to avoid tolerance
Topical Ointments
MUST:
1.
2.
Instruct the client to remove the ointment on the skin from the previous dose
Avoid hairy areas. Cover with plastic wrap. Rotate sites.
NITRATES are administered every ___ but not more than ___ tablets
5 minutes; 3
Replace drug approximately every
6 mos
Inhibit sympathetic stimulation of beta-receptors in the heart
+ Decrease heart rate and force of myocardial contraction
Beta-adrenergic blocking agents
Propranolol
Metoprolol
Nadolol
Timolol
Acebutolol
Betaxolol
Esmolol
Pindolol
Penbutolol
Reduces frequency and severity of acute anginal attacks, dysrhythmias
Weigh daily. Report weight gain of
5 lbs or greater
Prevent the movement of extracellular calcium into the cell resulting in coronary and peripheral artery dilation
Calcium-Channel Blockers
Calcium-Channel Blockers USES
Stable angina
Dysrhythmias
Hypertension
Verapamil
Nifedipine
Diltiazem
Nicardipine
Felodipine
Calcium-Channel Blockers
Dopamine & Dobutamine USES
hypovolemic and cardiogenic shock
Epinephrine USES
anaphylactic shock
Inotrope
Increases cardiac contractility
Chronotrope
Increases heart rate
Dromotrope
Increases AV conduction
Disrupt the blood coagulation process
+ Thereby suppressing the production of fibrin
ANTICOAGULANTS
Heparin
Warfarin
Anti-coags
ANTICOAGULANTS USES
Pulmonary embolism, DVT, MI, A-Fib
Heparin: Monitor ___
Therapeutic levels:
aPTT (activated partial thromboplastin time)
1.5 to 2.5 (25 to 38 seconds)
Parenteral (SQ) Coumadin/Warfarin: Monitor ____
Therapeutic levels INR:
PT (Prothrombin time)
INR: 2.0 to 3.0
ANTIDOTES
Heparin:
Warfarin: Vitamin K
Protamine sulfate
Vitamin K
Report any signs of
BLEEDING
Prevent abnormal heart rhythms
ANTI-DYSRHYTMICS
Quinidine
Procainamide
Lidocaine
Flecainide
Class I (Sodium Channel
Blockers)
Acebutolol
Propranolol
Esmolol
Class II (Beta Blockers)
Bretylium
Amiodarone
Class III (Conduction
Delayers)
Verapamil
Diltiazem
Nifedipine
Class IV (Calcium – channel
Blockers)
Treat abnormalities in cardiac rate and rhythm
ANTI-DYSRHYTMICS
BEST to monitor for dysrhythmias
ECG