Gastroenterology Flashcards
In the setting of portal hypertension, what are he indications to cease beta blockers?
BP <90
AKI
Na <120
What is the gold standard test for dx of primary sclerosing cholangitis?
ERCP demonstrating strictures of biliary tree
What does lactulose do to the pH of the colon?
Increases colon pH
What are the most common presenting symptoms with ZE syndrome?
Abdominal pain
Diarrhoea
Bleeding
What is the treatment of ZE Syndrome without MEN1?
Laparotomy and resection with curative intent
High dose PPI
In the setting of paracetamol toxicity, what features of the Kings College Criteria indicate the need to proceed to transplantation?
pH <7.3
OR
INR >6.5, creat >300, encephalopathy
What are the features of the Kings College Criteria for liver tx in paracetamol toxicity?
pH <7.3
INR >6.5
Creat >300
Grade 3/4 encephalopathy
Extra:
Lactate >3 after 12 hrs of fluid
Phosphate >3.75 at 2-4 days
What is the accepted definition of precore mutant hepatitis b?
Hep B e antigen negative
Anti HBe antibody positive
Detectable hbv DNA
What do parietal cells do?
Secrete acid and If
What do D cells secrete?
Somatostatin (inhibitor)
What do chief cells produce?
Pepsinogens and zymogens
What do g cells produce?
Gastrin
What antibody is generally positive in PSC?
P anca
What antibody is generally positive in PBC?
AMA
ANA
What antibody is generally positive in type 1 autoimmune hepatitis?
Anti SMA
P Anca
Ana
Ama
