Gastro-oesophageal reflux disease

Question 1

Symptoms

Answer 1

• Heartburn
• Unpleasant taste

Question 2

Cause

Answer 2

• Drug side effect: NSAID, nitrate, bisphosphonate, CCB, corticosteroid, alpha blocker, anti-muscarinic, bblocker, TCA
• Pregnancy

Question 3

Treatment: uninvestigated GORD

Answer 3

PPI 4 weeks
- H pylori test → if positive: eradication therapy
- High risk ppt: elderly, north africans + certain are

Question 4

Treatment: severe oesophagitis

Answer 4

PPI 8 weeks

Question 5

Treatment: endoscopy confirmed

Answer 5

PPI 4 or 8 weeks OR H2 receptor antagonist

Question 6

Treatment: pregnancy

Answer 6

First line: diet + lifestyle → antacids → omeprazole (severe symptoms)