Gastro and Urinary Flashcards
What is enuresis defined as
Involuntary discharge of urine by day or night in a child over 5 in the absense of congenital or acquired defects of the NS or urinary tract
How is nocturnal enuresis categorised
Primary- never achieved continence
Secondary- child had been dry for at least 6 months
Management of enuresis
Rule out other causes
General adive- fluid intake, empty bladder before bed and during day
Reward system- eg star chart for going toilet before bed and not for a dry night
Then- Enuresis alarm
Then- desmopressin
When would use desmopressin for enuresis
Short term control needed- sleepoves
Enuresis alarm not effective or acceptable
Examination findings of testicular torsion
Swollen testicle
Absent cremasteric reflex
Elevation of testicle worsens pain
What causes threadworms
Enterobius vermicularis
Infestation occurs after swallowing eggs in the environment
How can threadworms be investigated
Could put piece of tape over anus and then do MCS
Management of threadworms
Under 6 months- hygiene measures for 6 weeks (same if pregnant or breastfeeding)
6 months- 2 years- piperazine single dose
Over 2 years- Single does of mebendazole with hygiene measures for 2 weeks if over 2 years
Consider treating whole family too
If infection persists over 2 weeks/6 weeks treat again
What is hirschprungs disease
Presence of aganglionic segement of bowel from developmental failure of parasympathetic Auerbach (myenteric) and meissner (submucosal) plexuses
Presentation of hirschprungs disease
Failure to pass meconium in first 24 hours
Bilious vomiting
Abdo distension
Constipation mixed with overflow diarrhoea
Complications of hirschprungs disease
Enterocolitis
Perofration
Meconium plug syndrome
Initial investigation for hirschprungs and diagnostic
AXR if obstruction
Full thickness rectal biopsy
Treatment for hirschprungs
Bowel irrigation initially- can be barium enema
Transanal endorectal pull through
Risk factors for hirshcprung disease
Trisomy 21
Male
MEN2A
Risk factors for GORD
Preterm delivery
Neuro disorders
Presentation of GORD
Vomiting of feeds
Develops before 8 weeks typically
Alongside
- arching of back
- irrittable
- crying
When should arrange same day referral for GORD
Haematemesis
Melaena
Dysphagia
When should arrange a specialist assessment by paediatrician GORD
Uncertain diagnosis
Growth issues
Unexplained distress in those with communication difficulty
Not responding to treatment
Avoiding food
Unexplained IDA
No improvement in GORD after a year
Sandifers syndrome suspected
Recurrent aspiration pneumonia
Upper airway erosion
Dental erosion in child with neurodisability
Recurrent otitis media (more than 3 episodes in 6 months)
Management of GORD in child breastfeeding
- Breastfeeding assessment and advice
- 1-2 week trial of alginate therapy- if symptoms improve after 2 weeks continue the therapy. Stop at regular intervals to see if symptoms have improved
If have not then medical treatment
Mangement of GORD in formula fed
- Reduce volume of milk if excessive (150ml a day per kg)
- Offer 1-2 weeks of smaller more frequent unless they already are small and frequent
- 1-2 weeks of feed thickeners
- Alginate therapy
- Medical management
Medical management of GORD
4 week suspension of omeprazole
If doesnt work refer for possible endoscopy and potential metoclopramide treatment
Complications of GORD
Distress
FTT
Aspiration
Frequent otitis media
Dental erosion in older children
When does pyloric stenosis typically present
2nd-4th week of life
What causes pyloric stenosis
Hypertrophy of smooth circular muscles of pylorus
Risk factors for pyloric stenosis
Male
Positive family history
First born child
Turners syndrome
Examination finding of pyloric stenosis
Palpable olive epigastric mass
Dehydration
Visible peristalsis
Blood gas finding of pyloric stenosis
Hypochloraemic, hypokalaemic alkalosis but can become dehydrated lactic acidosis
Presentation of pyloric stenosis
Projectile vomiting 30 mins after feed
Constipation and dehydration
How is pyloric stenosis diagnosed
Test feed where look for visible peristalsis
US- target lesion over 3mm
Hos is pyloric stenosis managed
Treat fluid and electrolyte loss
NG tube
Ramstedt pyloromyotomy
Chronic diarrhoea differentials in a child
Cows milk intolerance
Toddler diarrhoea
Coeliac disease
Lactose intolerance
How does lactose intolerance present
Abdo pain and bloating linked to dairy eating
Diarrhoea
How can an upper UTI be diagnosed in a child
2 ways
- fever over 38 and bacteriuria
- fever under 38, bacteriurua and loin pain/tenderness
What to do if upper UTI suggested in child
Depending on severity send urine for MCS and if severe consider referral
What do if UTI suspected in under 3 months
Refer to paediatrics with parenteral abx
What do if UTI suspected in child over 3 months
Perform dipstick
What do if in child leukocyte and nitrite positive
Start treatment
Send a culture if recurrent UTIs, suspect upper UTI, no response in 48 hours to treatment
What to do in child if leukocyte pos and nitrite negative
Under 3 start abx and send for culture- reassess after
Over 3 only start abx if really suspect UTI
What to do in child if leukocyte neg and nitrite pos
Start abx and send for culture
Which 2 abx are available for upper UTI
Co-amoxiclav or cefalexin depending on sensitivity
Referral depends on severity
Children older than 3 months with UTI treatment
1st line- trimethoprim (if there is low risk of resistance), or nitrofurantoin (if eGFR ≥ 45ml/minute)
2nd line- nitrofurantoin (if eGFR ≥ 45ml/minute) if it has not been used as a first-line option, amoxicillin (only if culture results available and susceptible), or cefalexin.
Potentially do an US if indicated
When prescribing nitrodurantoin to over 3 months what is important criteria
eGFR over 45
When is an US indicated in UTI DURING the infection
In all children
- poor urinary flow
- abdo or bladder mass
- sepsis
- raised creatinine
- does not respond within 48 hours
- non-ecoli
If under 6 months with recurrent UTI
When is an US indicated in UTI 6 weeks after the infection
Children aged 6 months or older with recurrent UTI
Children under 6 months with first time UTI that responds to treatment
When is DMSA and MCUG scan indicated 6 months after UTI
If under 3 years and atypical or recurrent UTI
If over 3 years and recurrent UTI
What defines recurrent UTI
2 upper UTI episodes
1 upper and 1 lower UTI episode
3 lower episodes
What is done if somone has recurrent UTIs
Prophylactic abx which depends on local resistance
First line- trimethoprin and nitro
Second line- cefalexin and amoxicillin
If under 6 months do US during the infection
If over 6 months do in 6 weeks
Do a DMSA scan within 6 months
Presentation of wilms tumour
Abdo mass
Painless haematuria
Flank pain
Anorexia and fever
Where does wilm tumour most commonly metastasise
The lung
What do with unexplained enlarged abdo mass in achild
Refer for paediatric review in 48 hours
How are nephroblastomas imaged
USS intitally then CT NOT Biospy
Management of wilms tumour
Nephrectomy and chemo
Radiotherapy if advanced
Associations of Wilms tumour
Beckwith-Wiedemann syndrome
WAGR
Loss of function mutation in the WT1 gene chromosome 11
What is included in WAGR syndrome
Wilms tumour, Aniridia, Genitourinary malformations, mental Retardation
Management of undescended testes
Unilateral
- Patient should be referred from around 3 months seeing a urological surgeon by 6 months of age
- if bilateral reveiwed within 24 hours as needs urgent genetic or endocrine investigation
What is hypospadias
Congenital abnormality of the urethral opening- appears with ventral urethral meatus
How can hypospadias be identified
Newborn check
Abnormal urine flow noticed by parent
Examination findings of hypospadias
Ventral urethral meatus
Hooded prepuce (where foreskin wide open)
Ventral curvature of the penis
Management of hypospadias
Refer to specialists
Operation at 12 months
Can’t be circumcised
If very distal may not need operation
Associated conditions of hypospadias
Inguinal hernia
Cryptochordism
How does meckels diverticulum present
Rectal bleeidng
Abdo pain like appendicitisi
What determines the initial investigation for meckels diverticulum
If haem stable technietium99
If not and needed transfusion- arteriography
Managment of meckels diverticulum
Surgical- wedge excision or resection
What are differences between gastrochisis and ampholacele
Gastrochisis is lateral to umbilicus whereas ampholacele is through umbilicus
Ampholacele has a thin sac whereas gastrochisis is just the organs
Gastrochisis is vaginal delivery versus C section in ampholacele to preserve the sac
Gastrochisis requires surgery within 4 hours but ampholacele surgery done in stages
Gastrochisis associated with smoking and low scoioeconomic status whereas ampholacele associated with downs, kidney and cardiac abnormalities
Features indicative of idiopathic constipation
Meconium passed within 48 hours of birth (in a full-term baby).
Onset of constipation at least a few weeks after birth.
Presence of precipitating factors:
- Dietary factors (for example changes to infant formula or weaning, poor diet, or insufficient fluid intake).
- Acute illness, such as infection.
- Anal fissure.
- Use of drug treatments such as sedating antihistamines or opiates.
- Timing of potty or toilet training.
- Psychosocial factors such as difficulty accessing a toilet, moving house, starting nursery or school, other major change in family circumstances, and fears and phobias
What to do if amber and red signs in constipation history
Red- refer immediately to specialist and do not treat immediately
Amber- refer for specialist help (2 weeks) and can treat in meantime
Red flag features for constipation
Symptoms of constipation appearing from birth or during the first few weeks of life — may indicate Hirschsprung’s disease
Delay in passing meconium for more than 48 hours after birth, in a full-term baby
Abdominal distention with vomiting
Family history of Hirschsprung’s disease
Ribbon stool pattern
Leg weakness or motor delay
Examination may reveal unexplained lower limb deformity or abnormal neuromuscular signs, including abnormal reflexes.
Abnormal appearance of the anus
Abnormalities in the lumbosacral and gluteal regions
Amber features for constipation
Evidence of faltering growth, developmental delay, or concerns about wellbeing, which may indicate a systemic condition - coeliac disease, hypothyroidism, cystic fibrosis, and electrolyte disturbance
Constipation triggered by the introduction of cows’ milk
Concern of possible child maltreatment — follow local child safeguarding procedures.
What does ribbon stools suggest
Anal stenosis- typically in infants
Umbilical hernias in children
Very normal and will often resolve by 3 years
Management is obervation
Features which suggest sexual abuse in a child
pregnancy
sexually transmitted infections, recurrent UTIs
sexually precocious behaviour
anal fissure, bruising
reflex anal dilatation
enuresis and encopresis
behavioural problems, self-harm
recurrent symptoms e.g. headaches, abdominal pain
Who is most likely person to sexually abuse a child
Father
Unrelated man
Older brother
What is position of appendix if obturator sign present
Pelvic
Most common position of appendix
Retrocaecal
How does oesophageal atresia present
Drooling
Gags and chokes when feeding
Cough
Cyanotic
Investigations for oesophageal atresia/TOF
NG tube aspiration with CXR
Gastrogaffin swallow is gold standard
Complications of oesophageal atresia and TOF
Aspiration of food
Acid in the lungs causing CLD
What is faecal impaction and how does it present
When there is a large faecal mass in the rectum
Presents with
- severe constipation symptoms
- overflow sx like soiling
- large mass on palpation
Management of faecal disimpaction
Macrogol and review after 1 week
If after 2 weeks does not work use stimulant laxative like Senna
If does not work refer to specialist
If not tolerant of macrogol use senna and if the stools are hard add lactulose or docusate
Management of constipation
Macrogol (drug depends on age) If over 12 Mavicol, if under mavicol paediatric
If not tolerated use senna and add lactulose if not tolerated
If does not improve use Senna however if get diarrhoea reduce dose
When to refer gastroenteritis
Bilious vomiting/difficult to control vomiting
Blood in stool
Severe dehydration/shock
HUS
How is giardia treated
Tinidazole