Gastro and Urinary Flashcards

1
Q

What is enuresis defined as

A

Involuntary discharge of urine by day or night in a child over 5 in the absense of congenital or acquired defects of the NS or urinary tract

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2
Q

How is nocturnal enuresis categorised

A

Primary- never achieved continence
Secondary- child had been dry for at least 6 months

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3
Q

Management of enuresis

A

Rule out other causes
General adive- fluid intake, empty bladder before bed and during day
Reward system- eg star chart for going toilet before bed and not for a dry night
Then- Enuresis alarm
Then- desmopressin

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4
Q

When would use desmopressin for enuresis

A

Short term control needed- sleepoves
Enuresis alarm not effective or acceptable

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5
Q

Examination findings of testicular torsion

A

Swollen testicle
Absent cremasteric reflex
Elevation of testicle worsens pain

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6
Q

What causes threadworms

A

Enterobius vermicularis
Infestation occurs after swallowing eggs in the environment

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7
Q

How can threadworms be investigated

A

Could put piece of tape over anus and then do MCS

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8
Q

Management of threadworms

A

Under 6 months- hygiene measures for 6 weeks (same if pregnant or breastfeeding)
6 months- 2 years- piperazine single dose
Over 2 years- Single does of mebendazole with hygiene measures for 2 weeks if over 2 years
Consider treating whole family too
If infection persists over 2 weeks/6 weeks treat again

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9
Q

What is hirschprungs disease

A

Presence of aganglionic segement of bowel from developmental failure of parasympathetic Auerbach (myenteric) and meissner (submucosal) plexuses

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10
Q

Presentation of hirschprungs disease

A

Failure to pass meconium in first 24 hours
Bilious vomiting
Abdo distension
Constipation mixed with overflow diarrhoea

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11
Q

Complications of hirschprungs disease

A

Enterocolitis
Perofration
Meconium plug syndrome

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12
Q

Initial investigation for hirschprungs and diagnostic

A

AXR if obstruction
Full thickness rectal biopsy

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13
Q

Treatment for hirschprungs

A

Bowel irrigation initially- can be barium enema
Transanal endorectal pull through

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14
Q

Risk factors for hirshcprung disease

A

Trisomy 21
Male
MEN2A

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15
Q

Risk factors for GORD

A

Preterm delivery
Neuro disorders

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16
Q

Presentation of GORD

A

Vomiting of feeds
Develops before 8 weeks typically
Alongside
- arching of back
- irrittable
- crying

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17
Q

When should arrange same day referral for GORD

A

Haematemesis
Melaena
Dysphagia

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18
Q

When should arrange a specialist assessment by paediatrician GORD

A

Uncertain diagnosis
Growth issues
Unexplained distress in those with communication difficulty
Not responding to treatment
Avoiding food
Unexplained IDA
No improvement in GORD after a year
Sandifers syndrome suspected
Recurrent aspiration pneumonia
Upper airway erosion
Dental erosion in child with neurodisability
Recurrent otitis media (more than 3 episodes in 6 months)

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19
Q

Management of GORD in child breastfeeding

A
  1. Breastfeeding assessment and advice
  2. 1-2 week trial of alginate therapy- if symptoms improve after 2 weeks continue the therapy. Stop at regular intervals to see if symptoms have improved
    If have not then medical treatment
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20
Q

Mangement of GORD in formula fed

A
  1. Reduce volume of milk if excessive (150ml a day per kg)
  2. Offer 1-2 weeks of smaller more frequent unless they already are small and frequent
  3. 1-2 weeks of feed thickeners
  4. Alginate therapy
  5. Medical management
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21
Q

Medical management of GORD

A

4 week suspension of omeprazole
If doesnt work refer for possible endoscopy and potential metoclopramide treatment

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22
Q

Complications of GORD

A

Distress
FTT
Aspiration
Frequent otitis media
Dental erosion in older children

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23
Q

When does pyloric stenosis typically present

A

2nd-4th week of life

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24
Q

What causes pyloric stenosis

A

Hypertrophy of smooth circular muscles of pylorus

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25
Risk factors for pyloric stenosis
Male Positive family history First born child Turners syndrome
26
Examination finding of pyloric stenosis
Palpable olive epigastric mass Dehydration Visible peristalsis
27
Blood gas finding of pyloric stenosis
Hypochloraemic, hypokalaemic alkalosis but can become dehydrated lactic acidosis
28
Presentation of pyloric stenosis
Projectile vomiting 30 mins after feed Constipation and dehydration
29
How is pyloric stenosis diagnosed
Test feed where look for visible peristalsis US- target lesion over 3mm
30
Hos is pyloric stenosis managed
Treat fluid and electrolyte loss NG tube Ramstedt pyloromyotomy
31
Chronic diarrhoea differentials in a child
Cows milk intolerance Toddler diarrhoea Coeliac disease Lactose intolerance
32
How does lactose intolerance present
Abdo pain and bloating linked to dairy eating Diarrhoea
33
How can an upper UTI be diagnosed in a child
2 ways - fever over 38 and bacteriuria - fever under 38, bacteriurua and loin pain/tenderness
34
What to do if upper UTI suggested in child
Depending on severity send urine for MCS and if severe consider referral
35
What do if UTI suspected in under 3 months
Refer to paediatrics with parenteral abx
36
What do if UTI suspected in child over 3 months
Perform dipstick
37
What do if in child leukocyte and nitrite positive
Start treatment Send a culture if recurrent UTIs, suspect upper UTI, no response in 48 hours to treatment
38
What to do in child if leukocyte pos and nitrite negative
Under 3 start abx and send for culture- reassess after Over 3 only start abx if really suspect UTI
39
What to do in child if leukocyte neg and nitrite pos
Start abx and send for culture
40
Which 2 abx are available for upper UTI
Co-amoxiclav or cefalexin depending on sensitivity Referral depends on severity
41
Children older than 3 months with UTI treatment
1st line- trimethoprim (if there is low risk of resistance), or nitrofurantoin (if eGFR ≥ 45ml/minute) 2nd line- nitrofurantoin (if eGFR ≥ 45ml/minute) if it has not been used as a first-line option, amoxicillin (only if culture results available and susceptible), or cefalexin. Potentially do an US if indicated
42
When prescribing nitrodurantoin to over 3 months what is important criteria
eGFR over 45
43
When is an US indicated in UTI DURING the infection
In all children - poor urinary flow - abdo or bladder mass - sepsis - raised creatinine - does not respond within 48 hours - non-ecoli If under 6 months with recurrent UTI
44
When is an US indicated in UTI 6 weeks after the infection
Children aged 6 months or older with recurrent UTI Children under 6 months with first time UTI that responds to treatment
45
When is DMSA and MCUG scan indicated 6 months after UTI
If under 3 years and atypical or recurrent UTI If over 3 years and recurrent UTI
46
What defines recurrent UTI
2 upper UTI episodes 1 upper and 1 lower UTI episode 3 lower episodes
47
What is done if somone has recurrent UTIs
Prophylactic abx which depends on local resistance First line- trimethoprin and nitro Second line- cefalexin and amoxicillin If under 6 months do US during the infection If over 6 months do in 6 weeks Do a DMSA scan within 6 months
48
Presentation of wilms tumour
Abdo mass Painless haematuria Flank pain Anorexia and fever
49
Where does wilm tumour most commonly metastasise
The lung
50
What do with unexplained enlarged abdo mass in achild
Refer for paediatric review in 48 hours
51
How are nephroblastomas imaged
USS intitally then CT NOT Biospy
52
Management of wilms tumour
Nephrectomy and chemo Radiotherapy if advanced
53
Associations of Wilms tumour
Beckwith-Wiedemann syndrome WAGR Loss of function mutation in the WT1 gene chromosome 11
54
What is included in WAGR syndrome
Wilms tumour, Aniridia, Genitourinary malformations, mental Retardation
55
Management of undescended testes
Unilateral - Patient should be referred from around 3 months seeing a urological surgeon by 6 months of age - if bilateral reveiwed within 24 hours as needs urgent genetic or endocrine investigation
56
What is hypospadias
Congenital abnormality of the urethral opening- appears with ventral urethral meatus
57
How can hypospadias be identified
Newborn check Abnormal urine flow noticed by parent
58
Examination findings of hypospadias
Ventral urethral meatus Hooded prepuce (where foreskin wide open) Ventral curvature of the penis
59
Management of hypospadias
Refer to specialists Operation at 12 months Can't be circumcised If very distal may not need operation
60
Associated conditions of hypospadias
Inguinal hernia Cryptochordism
61
How does meckels diverticulum present
Rectal bleeidng Abdo pain like appendicitisi
62
What determines the initial investigation for meckels diverticulum
If haem stable technietium99 If not and needed transfusion- arteriography
63
Managment of meckels diverticulum
Surgical- wedge excision or resection
64
What are differences between gastrochisis and ampholacele
Gastrochisis is lateral to umbilicus whereas ampholacele is through umbilicus Ampholacele has a thin sac whereas gastrochisis is just the organs Gastrochisis is vaginal delivery versus C section in ampholacele to preserve the sac Gastrochisis requires surgery within 4 hours but ampholacele surgery done in stages Gastrochisis associated with smoking and low scoioeconomic status whereas ampholacele associated with downs, kidney and cardiac abnormalities
65
Features indicative of idiopathic constipation
Meconium passed within 48 hours of birth (in a full-term baby). Onset of constipation at least a few weeks after birth. Presence of precipitating factors: - Dietary factors (for example changes to infant formula or weaning, poor diet, or insufficient fluid intake). - Acute illness, such as infection. - Anal fissure. - Use of drug treatments such as sedating antihistamines or opiates. - Timing of potty or toilet training. - Psychosocial factors such as difficulty accessing a toilet, moving house, starting nursery or school, other major change in family circumstances, and fears and phobias
66
What to do if amber and red signs in constipation history
Red- refer immediately to specialist and do not treat immediately Amber- refer for specialist help (2 weeks) and can treat in meantime
67
Red flag features for constipation
Symptoms of constipation appearing from birth or during the first few weeks of life — may indicate Hirschsprung's disease Delay in passing meconium for more than 48 hours after birth, in a full-term baby Abdominal distention with vomiting Family history of Hirschsprung's disease Ribbon stool pattern Leg weakness or motor delay Examination may reveal unexplained lower limb deformity or abnormal neuromuscular signs, including abnormal reflexes. Abnormal appearance of the anus Abnormalities in the lumbosacral and gluteal regions
68
Amber features for constipation
Evidence of faltering growth, developmental delay, or concerns about wellbeing, which may indicate a systemic condition - coeliac disease, hypothyroidism, cystic fibrosis, and electrolyte disturbance Constipation triggered by the introduction of cows' milk Concern of possible child maltreatment — follow local child safeguarding procedures.
69
What does ribbon stools suggest
Anal stenosis- typically in infants
70
Umbilical hernias in children
Very normal and will often resolve by 3 years Management is obervation
71
Features which suggest sexual abuse in a child
pregnancy sexually transmitted infections, recurrent UTIs sexually precocious behaviour anal fissure, bruising reflex anal dilatation enuresis and encopresis behavioural problems, self-harm recurrent symptoms e.g. headaches, abdominal pain
72
Who is most likely person to sexually abuse a child
Father Unrelated man Older brother
73
What is position of appendix if obturator sign present
Pelvic
74
Most common position of appendix
Retrocaecal
75
How does oesophageal atresia present
Drooling Gags and chokes when feeding Cough Cyanotic
76
Investigations for oesophageal atresia/TOF
NG tube aspiration with CXR Gastrogaffin swallow is gold standard
77
Complications of oesophageal atresia and TOF
Aspiration of food Acid in the lungs causing CLD
78
What is faecal impaction and how does it present
When there is a large faecal mass in the rectum Presents with - severe constipation symptoms - overflow sx like soiling - large mass on palpation
79
Management of faecal disimpaction
Macrogol and review after 1 week If after 2 weeks does not work use stimulant laxative like Senna If does not work refer to specialist If not tolerant of macrogol use senna and if the stools are hard add lactulose or docusate
80
Management of constipation
Macrogol (drug depends on age) If over 12 Mavicol, if under mavicol paediatric If not tolerated use senna and add lactulose if not tolerated If does not improve use Senna however if get diarrhoea reduce dose
81
When to refer gastroenteritis
Bilious vomiting/difficult to control vomiting Blood in stool Severe dehydration/shock HUS
82
How is giardia treated
Tinidazole
83
When can go back to school with HUS
2 consecutive negative samples 24 hours apaprt
84
How are viral gastroenteritises diagnosed
Stool electron microscopy
85
Managment of primary enuresis with daytime symptoms
Refer all children with daytime symptoms to enuresis clinic
86
Management of secondary bedwetting
Urinalysis and constipation checks If no cause found refer
87
How can volvulus present
Bilious vomiting and severe pain/irritability Blood in stool is late stage of ischaemia
88
How does autosomal recessive PCKD present
Presents perinatally and most of time will be dead by 12 months Renal cysts with subsequent renal and hepatic fibrosis Renal failure too
89
Complications of autosomal recessive PCKD
Oligohydramnios leading to pulmonary hypoplasia
90
Treatment for hyperconjugated hyperbilirubinaemia
Ursodeoxycolic acid
91
Causes of hyperconjugated bilirubinaemia
Biliary atresia Choledochal cysts
92
Risks of gastrochisis
Dehydration and shock from fluid loss Malrotation
93
Management of gastrochisis
Place cling film over bowels Surgery within a few hours except for if signs of impaired bowel perfusion
94
Presentation of enterocolitis in hirschprungs
Abdo pain Blood in stool Fever
95
First line for intussusception
Air insufflation then surgical intervention
96
Complications of minimal change disease
Recurrent infections Increased thrombosis risk Hypercholesterolaemia
97
What causes bloating and diarrhoea post gastroenteritis
Is normal to get a post infectious IBS when normal diet reintroduced
98
Infections that can precede mesenteric adenitis
URTI Gastroenteritis most commonly Yersinia
99
What can cause recurrent intussusception
Meckels diverticulum
100
What is most common cause of acute scrotum in children
Hydatid torsion
101
What is hydatid torsion
Twisting of testicular appendage which is a remnant of the muellerian tube
102
Presentation of hydatid torsion
Pain over a few days (not acute) Swelling Cremasteric reflex present Blue dot sign Tender at top of testicle not whole testicle
103
Presentation of epididymitis
Dysuria or discharge Pain and swelling of the testicle Prehns and cremasteric positive
104
How to investigate an acute scrotum
Doppler is best way to assess testicular blood flow Surgical exploration is necessary if cant exclude torsion
105
Complications of undescended testicles
Testicular torsion Infertility Testicular cancer
106
What are the types of TOF
Type A- no connection between proximal and distal oesophagus Type B- fistula between proximal oesophagus to trachea Type C- fistula between distal oesophagus to trachea Type D- fistula between proximal and distal oesophagus to trachea Type E- normal oesophagus connection but fistula to trachea too
107
First line and definitive management of oesophageal atresia and TOF
Repogle tube to drain the saliva Surgical management
108
What is blue dot sign
Blue dot on testicle caused by hydatid torsion typically
109
Triad for nephrotic syndrome
Oedema- normally periorbital or sacral Hypoalbuminaemia- >25g/L Proteinuria- 3g/24 hour or PCR over 15/mg/mmol
110
Complications of nephrotic syndrome
Hyperlipidaemia Thrombosis Pneumooccocal risk Hypovolaemia
111
Treatment of hypovolaemia in nephrotic syndrome
IV albumin
112
Most common cause of nephrotic syndrome in a child
Minimal change disease
113
Treatment of minimal change disease
Oral pred and then reduce the dose over time
114
Causes of nephrotic syndrome in children
Minimal change disease Focal segemental glomerulosclerosis Mesangiocapillary glomerulonephritis Membranous nephropathy
115
Steroid resistant causes of nephrotic syndrome
Focal segmental glomerulosclerosis- most common Mesangiocapillary glomerulonephritis Membranous nephropathy
116
Low complement levels Haematuria Renal function declining over many years Older children
Mesangiocapillary glomerluonpehritis
117
What do if fail to cure minimal change disease
Biopsy
118
Biopsy finding of minimal change disease
Diffuse loss of podocytes
119
Causes of membranous nephropathy
Hep B
120
Benign causes of proteinuria
Transient- febrile illness or after exercise Orthostatic- common if upright all of the day
121
Triad for nephritic syndrome
Hypertension Haematuria Oedema (with oligouria)
122
Difference between red and brown coloured urine
Red- lower tract bleed Brown- glomerular pathology as broken down into casts
123
Problems of glomerulonephritis
Loss of barrier function- blood or protein lost Loss of filtering capacity- accumulation of toxins
124
Causes of glomerulonephritis
IgA nephropathy- most common HSP Anti-glomerular basement membrane (Goodpastures) Post streptococcal
125
Difference between IgA nephropathy, HSP and post streptococcal
IgA and HSP within a few days Post streptococcal within a month HSP is in essence a systemic version of IgA nephropathy
126
What can precede intussusception
Coryzal illness Tummy bug
127
What are associated with malrotation
Congenital diaphragmatic hernia Exomphalos
128
Investigation for anti GBM
IgG type IV lung and kidney
129
Haemoptysis and haematuria cause of AKI
Anti-GBM
130
Hearing and vision loss with haematuria
Alports syndrome
131
How does rhabdomyolysis present
Dark urine Muscle pain Signs of hyperkalaemia
132
Blood findings of rhabdomyolysis
Hyperkalaemia Increased CK
133
What is complication of a renal scar
HTN- may need monitoring regularly
134
How is severeity of UC classified
Either true love and witts or paediatric ulcerative colitis activity index Categorised into mild, moderate and severe
135
Management of active UC
Mild to moderate - topical aminosalicylates for 4 weeks - if dont work use oral - can use steroids too if ineffective (topical or oral) Moderate to severe - infliximab, adalimumab
136
How to maintain remission in UC
Oral aminosalicylate Consider oral azathioprine or oral mercatopurine
137
What is monitored in children with UC and crohns
Vitamins and anaemia Growth Bone density Sigmoidoscopy to screen for adenocarcinoma in UC
138
Managment of active crohns
Induction of remission - oral glucocorticoid If more than 1 exacerbation a year or can increase glucorticoid dose, add azathioprine or mercatopurine If these are contraindicated add methotrexate
139
Maintaing remission in crohns
Azathioprine or mercatopurine If fails/contraindicated then use methotrexate
140
Complications of UC
Toxic megacolon Erythema nodosum PSC Haemorrhage Cancer
141
Differences between UC and crohns
Crohns affects all layers, UC mucosa and submucosa Crohns affects mouth to anus, UC distal to proximal spread
142
When refer with bedwetting
If have daytime symptoms then refer If secondary bedwetting after have ruled out UTI, DM and anxiety Primary if 2 rounds of treatment have not worked
143
What could cause secondary bedwetting
UTI DM Electrolyte abnormalities- hypokalaemia, hypercalcaemia Anxiety
144
What is management of inguinal hernias in children
Refer to paeds surgery ASAP
145
How does intussuception present
Bilious vomiting Screaming and crying Bringing knees up Red stool a late presentation
146
Guidelines for phimosis
If present under 2 is physiological- only refer when older than 2 years Do not forcibly retract as can cause scarring
147
Management of ballooning of foreskin during micurition in under 2
Can leave alone until 2 years old then avoid
148
Where is most common palpated site of intussuception
RUQ
149
MOst common site of intussusception
Ileo-caecal
150
investigation for intussusception
USS- showing mass Can also reveal free fluid and show ischaemia with colour doppler
151
When is air insufflation contraindicated and surgery recommended in intussusception
Peritonitis Perforation HSP- known complication
152
In post streptococcal glomerulonephritis what measure
C3, C4 and CH50 C3 very low and C4 normal
153
What conditions cause psot strep glomerulonephritis
Pharyngitis Impetigo
154
What is whirlpool on USS of childs abdomen suggestive of
Malrotation
155
Perianal fistula suggests what disease
Crohns
156
Conditions associated with intussusception
Lymphoma Gastroenteritis HSP
157
AXR findings of intussusception
paucity (less) of air in RUQ thickened wall (oedema) poorly defined liver edge dilated small bowel loops
158
Examination findings of intussusception
Sausage shaped mass Dances sign- emptiness on palpation in RLQ
159
What is a scaphoid abdomen and what seen in
Concave chest shape Seen in malrotation
160
Associations of malrotation
Congenital diaphragmatic hernia Omphalocele
161
Difference in cause of gastroenteritis- young child vs older
Young- viral (rotavirus) Older- bacterial (e coli)
162
Advice for toddlers diarrhoea
Encourage fibre intake
163
Management of lactose intolerance
Refer to dietician Encourage vit d and calcium intake
164
How do inguinal hernias present
Lump in testicle, maybe on crying/laughing On examination- can not get above it
165
How to treat umbilical granuloma
Salt
166
If have bilaterally undescended testes, what is ruled out
CAH Disorders of sexual differentiation
167
If on formula feeds, what is risk factor for gastroenteritis
Not sterilising water used to make up formula by boiling then cooling
168
Mass in groin area with severe vomiting and tense abdomen
Incarcerated hernia
169
Management of hepatitis A
Notify health protection agency Encourage fluid intake
170
Most common cause of delayed meconium passage
Meconium plug syndrome
171
Causes of HTN in a child
Renal - nephroblastoma - CKD - renal artery stenosis Cardiac - coarctation of aorta Metabolic - conns - phaeo - CAH
172
What is preferred BP measurement in a child
Manual
173
Management of 1 HTN reading in a child
Repeat
174
Flank mass causing HTN in a child
Neuroblastoma of adrenal medulla Measure urine catecholamine
175
Anuria and enlarged bladder in a child
Posterior urethral valve causes backflow of urine entering urethra
176
Other than renal problems what does AR PCKD do
Pulmonary hypoplasia Hepatic fibrosis
177
When is autosomal dominant PCKD picked up
Teenagers
178
What is operation for testicular torsion
Bilateral orchidopexy
179
Management of hydrocele in a child
Under 3 is fine- after if need to refer
180
What are these 3 signs for appendicitis - rosvings - cough - obturator
Rosvings- pain in RIF on left sided palpation Cough- pain on voluntary cough Obturator- pain on internal rotation when flex right thigh
181
How long are upper vs lower UTIs treated for in kids
Lower- 3 days Upper- 7 days
182
What is operation done for very severe GORD
Nissen fundoplication
183
How diagnose post strep glomerulonephritis
Anti-streptolysin titre C3 and C4 levels as C3 low
184
Imaging for wilms tumour
Initially do an USS Then a CT to stage
185
Best imaging for malrotation
Upper GI contrast
186
How do abdominal migraines present
Severe umbilical pain which can intterfere with daily life Associated with - headache - vomiting - photophobia - nausea - anorexia - pallor
187
What is difference between regurgitation, GOR and GORD
Regurgitation involves bringing it up after feed GOR= passage of stomach contents into oesophagus GORD= GOR with symptoms of irritation
188
What is a hydrocele
Collection of fluid within the tunica vaginalis
189
What is management of hydatid torsion
Exploratory surgery as need to rule out torsion
190
Management of undescended testicles
Bilateral - urgent endo review Unilateral - recheck at 6 wk baby check, then 4-5 months and if not refer to surgeons
191
Management of severe pyelonephritis
IV cefuroxime and gentamicin
192
If have TOF or oesophageal atresia what is another malformation these are associated with
Anal atresia
193
What do if measure childs bilirubin and is below phototherapy line but close
If unwell or 1 risk factor for neonatal jaundice keep in hospital and repeat in 18 hours If none and seems well then come back in 24 hours
194
Investigation for malrotation
Barium swallow
195
What skin changes can be seen in neuroblastoma
Blueberry papules
196
What investigation should be done on any child presenting with swelling or pain in testicle
USS to screen for cancer
197
How can a urine culture be done on an infant
Urine collection pads
198
Difference between neuroblastoma and nephroblastoma mass and presentation
In neuroblastoma will cross the midline Neuroblastoma with present with fever, weight loss, diarrhoea and vomiting- generally very unwell
199
How other than recurrent UTIs can VUR present
Enuresis Incontinence
200
How does mesenteric adenitis present
Post URTI - can be acute abdo pain - lymphadenopathy
201
How is mesenteric adenitis investigated
Abdo USS showing mesenteric thickening
202
What can precipitate transient proteinuria
Seizures Infections Pregnancy Exercise
203
What is risk of hydrocele
Inguinal hernias
204
What counts as daytime symptoms in a child
Wetting themselves Passing urine over 7x a day
205
Most sensitive investigation for intussusception
Contrast enema
206
Management of VUR
Refer to paediatric surgeons