Gastro

Question 1

PPIs indications

Answer 1

Dyspepsia
Peptic ulceration
Zollinger-Ellison syndrome

Question 2

PPI Side effects

Answer 2

Increased risk of fractures in elderly
Increased risk C.diff
Hyponatraemia
Hypomagnaesemia

Question 3

Orlistat indication

Answer 3

Lipase inhibitor

Adjunct to diet for weight loss if BMI>30 or >28 with other CVD risk

Question 4

Orlistat SEs

Answer 4

Abdominal discomfort
Loose, oily stools
Increased risk of UTIs

Question 5

Corticosteroids indications in Gastro

Answer 5

Acute inflammatory bowel disease

Question 6

Corticosteroids SEs

Answer 6

Adrenal axis suppression
Immunosuppression
Catabolic, hyperglycaemic, metabolic state
Osteoporosis
Hypomania and psychosis

Question 7

Aminosalicylates examples

Answer 7

Mesalazine

Sulfasalazine

Question 8

Aminosalicylates indications in Gastro

Answer 8

Acute inflammatory bowel disease

Maintenance of remission of IBD

Question 9

Peppermint oil indication

Answer 9

Antispasmodic

Relief of abdominal colic in IBS

Question 10

Peppermint oil SE

Answer 10

Local irritant

Question 11

Osmotic laxative example

Answer 11

Lactulose

Question 12

Lactulose SEs

Answer 12

Nausea
Vomiting
Abdominal discomfort

Question 13

Stimulant laxative example

Answer 13

Senna

Question 14

Senna SEs

Answer 14

Abdominal cramps

Risk of hypokalaemia with prolonged use