Malignant & Metabolic Disease Flashcards
1
Q
Anti-oestrogens
- Example
A
Tamoxifen
2
Q
Anti-oestrogens (tamoxifen)
- Indication
A
ER-positive breast cancer
Anovulatory infertility
3
Q
Anti-oestrogens (tamoxifen)
-side effects
A
- increased endometrial changes
- flushes
- PV bleeding
4
Q
Bisphosphonates
-examples
A
Alendronic acid, zolendronic acid, ibandronic acid
5
Q
Bisphosphonates
-indication
A
- treatment of osteoporosis
- prevention of steroid induced osteoporosis
6
Q
Bisphosphonates
-Mode of action
A
Osteoclasts inhibitors (slows the rate of bone turnover)
7
Q
Bisphosphonates
-side effects
A
- oesophagitis
- dyspepsia
- GI upset
- Atypical femoral fractures
- Osteonecrosis of the jaw