Gastric phase

Question 1

What are the three general functions of the stomach?

Answer 1

Question 2

What does the stomach do upon swallowing food?

Answer 2

Question 3

Describe the parts of the stomach and their function

Answer 3

Question 4

What are the cell types found in gastric glands?

Answer 4

Question 5

What are the functions and stimuli of G-cells?

Answer 5

Release gastrin -> directly stimulates gastric acid secretion from parietal cells
Release gastrin -> indirectly stimulates histamine release from ECL, which then stimulates parietal

Question 6

What is the function and stimuli of parietal cells?

Answer 6

Question 7

What are the functions of gastric acid

Answer 7

Question 8

How is acid secreted into the stomach

Answer 8

Dissociation of water is main mechanism
-Secondary converts CO2 and H2O to H+ and HCO3-

Question 9

How does gastrin change apical transporters in parietal cells

Answer 9

Vesicles are internalized in resting parietal cells

Question 10

Describe gastric digestive enzyme secretion

Answer 10

Chief cell releases gastric lipase and pepsinogen (digestive enzymes)
-Acid cleaves pepsinogen to pepsin, both cleave proteins to peptides

Question 11

Describe paracrine secretion

Answer 11

Question 12

Summarize long and short reflexes of the gastric phase

Answer 12

Question 13

What is the function and stimuli of mucus secretion

Answer 13

-Serve protective function from acid and pepsin from digesting epithelial cells

Question 14

What is a peptic ulcer

Answer 14