Gastric Carcinoma Flashcards
1
Q
Predisposing conditions for gastric carcinoma
A
- Correa’s hypothesis
- H. pylori
- EBV
- Gastric surgery
- Blood group
- familial predisposition
- Hereditary diffuse gastric cancer
- gastric polyps
- hypertrophic gastropathy
- gastric ulcer
- pernicious anaemia
2
Q
Lauren classification of adenocarcinomas in gastric cancer
A
- intestinal
- diffuse
- mixed
3
Q
Features of intestinal gastric carcinoma
A
- ulceration
- acinar formation
- in the antrum
4
Q
Features of diffuse gastric carcinoma
A
- constricting linitis plastica
- no acini
- in the fundus
- worse prognosis
5
Q
Presenting complaints for gastric carcinoma
A
- dyspepsia
- local complications (haemorrhage, obstruction, perforation)
- insidious (LOW, anaemia, mets)
6
Q
Differential diagnosis of dyspepsia
A
- functional
- PUD, gastritis
- GORD, oesophagitis
- drug side effects
- biliary disease
- gastric carcinoma
- other
7
Q
When is a history of dyspepsia significant?
A
When it has been present for more than 2 weeks
8
Q
Causes of gastric outlet obstruction
A
- gastric carcinoma
- peptic ulcer
- pancreatic pathology
- carcinoma/pseudocyst
- corrosive stricture
- rare things (volvulus/ bezoars)
9
Q
Clinical signs of gastric carcinoma
A
- epigastric mass
- Virchow-Trosier node (lymphatic spread)
- ascites and pelvic masses (peritoneal mets)
- paraneoplastic signs (seborrheic keratoses, acan thosis nigricans)
10
Q
Decision making with gastric carcinoma
A
- confirm histalogical diagnosis with endoscopic biopsy
- metastatic screen
- assess extent
- assess fitness for surgery
