Gastric Cancer Flashcards
1
Q
What is the incidence of gastric cancer in the UK?
A
23/100,000
2
Q
What is the male to famale ratio of gastric cancer?
A
male : female 2:1
3
Q
How do gastric cancers present?
A
- Dysepsia (vague abdo pain for 1 month and age 50+ —-> investigate)
- weight loss
- vomiting
- dysphagia
- anaemia
4
Q
What are the examination signs of gastric cancer?
A
- epigastric mass
- hepatomegaly
- jaundice
- ascites
- large left supraclavicular virchow’s node (trosiers sign)
- acanthosis nicrigans
5
Q
how does gastri cancer spread?
A
Local
lymphatic
blood borne
transcoelimic e.g to ovaries
6
Q
What tests are done for gastric cancer?
A
- gastro-oesophageal endoscopy with multiple edge ulcer biopsies
- endoscopic ultrasound to determine depth of cancer
- CT/MRI fro staging
- cytology of peritoneal washing to identify presence of peritoneal metastases.
7
Q
What is the treatment of gastric cancer?
A
- Partial or total gastrectomy
- combination chemotherapy (epirubicin, cisplatin, 5-fluorouracil)
- trageted therpies e.g. trastuzamab for HER2 positive tumours
8
Q
What is the 5yr survival rates of gastric cancer?
A
less than 10% overall 5 yr survival rates for gastric cancer but 20% for patients with radical gastric surgery.
9
Q
What is krukenberg tumour?
A
gastric cancer that spreads to the ovarians
