Gastic secretion Flashcards
How does the stomach participate in protein digestion>
acid hydrolysis and pepsin cleavage
How does the contents from the stomach enter the SI?
at a controlled rate to optizmize further digestion and absoprtion
Bezoar
ball of foreign material trapped in stomach (hairball)
Emesis
Vomiting, forcible ejection of stomach contents through the mouth
Dyspepsia
indigestion, pain in upper abdomen after eating
Gastroparesis
delayed emptying
Migrating Motor Complex
clears undigested material from the GI tract
Regurgitation
flow of material that has not reached the stomach back up the esophagus
Rugae
Stomach folds which expand as stomach fills
Scintigraphy
using a dual-radiolabeled solid and nutrient liquid meal, to measure gastric emptying
Trituration
grinding of food into small molecules
Paritel cell secretes
HCL, IF (for B12 absoprtion in the ileum)
Chief cells secrete
pepsinogen for protien digestion
surface mucous cells secrete
mucus, HCO3 fir gastroprotection
G cells in the antrum secrets
gastrin which activate parietall cells in the fundus to secrete acid
What kind of receptor does gastrin bind to
CCK2
what triggers gastrin release from the g cells in teh antrum?
seeing food or stomach distention causes vagal stimulation, causing gastrin releasing peptide, aromatic AA in the lumen
What activates parietal cells?
gastrin, histamine, and AcH
What activates ECL cells?
AcH, gastrin
ECL cells release what?
histamine which then binds to parietal cells