Gaseous Exchange and transport of O2 and CO2 Flashcards
Gaseous exchange
The movement of oxygen from the air into the blood and carbon dioxide from the blood into the air.
Law of partial pressures
Parcial pressure is the pressure exerted by an individual has that exists within a mixture of gasses.
Gas molecules always diffuse down a concentration gradient (high to low)
Gaseous exchange at alveoli (oxygen)
Partial pressure of oxygen is higher in alveoli than in capillaries surrounding alveoli.
Partial pressure of oxygen in blood is lower. So oxygen diffuses from alveoli into blood until pressure is equal.
Gaseous exchange at the alveoli (carbon dioxide)
Reverse of oxygen
Partial pressure of carbon dioxide in blood is higher than in alveoli so CO2 diffuses from capillaries to alveoli until pressure is equal.
Pulmonary diffusion works well because:
Big surface area to maximise diffusion
One cell thick - only short distance for gases to travel
Good blood supply - alveoli are covered in a network of capillaries- also the diameter of capillaries are less than a RBC so they must travel single file- maximising exposure to oxygen.
Gaseous exchange at muscles (oxygen)
Partial pressure of oxygen must be lower at the muscle than in the blood for diffusion to occur.
Lower partial pressure of oxygen allows oxygen to diffuse from blood to muscle until equilibrium is reached.
Gaseous exchange at muscles (CO2)
The partial pressure of CO2 must be lower in the blood than the muscle so it diffuses from muscle into the blood to be transported to the lungs.
What is the carrier of oxygen
Haemoglobin
O2 + haemoglobin
Oxyhaemoglobin
How is o2 transported in the blood
97% of o2 in blood combines with haemoglobin to form oxyhaemoglobin
3% dissolved into plasma
Muscles oxygen carrier is
Myoglobin
Myoglobin has …
A higher affinity for oxygen than haemoglobin.
How is carbon dioxide transported (lungs to muscle)
7% dissolves into plasma
23% combines with haemoglobin (carbaminohaemoglobin)
70% is transported as bicarbonate ions (hydrogen carbonate ions)
CO2 + haemoglobin =
Carbaminohaemoglobin
CO2 diffused in blood
It enters into RBCs and combines with water to form carbonic acid which splits into hydrogen carbonate and hydrogen ions.
The excess hydrogen ions are buffered by the haemoglobin to stop blood becoming too acidic.