Gas And Respiration Flashcards

1
Q

Movement of gases from one compartment to another plays an important role in? (4 points)

A
  • breathing and exchange of alveolar blood gases
  • cellular respiration
  • equipment used to aid breathing
  • physiological responses to altitude and underwater pressure
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2
Q

Passive movement follows what rule?

A

Standard diffusion rules, always from a higher pressure to a region of lower pressure

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3
Q

If the concentration gradient is larger what is faster?

A

The diffusion rate

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4
Q

What must gases do in order to diffuse across a biological membrane?

A

Dissolve in a liquid

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5
Q

Diffusion of oxygen is from…..?

A

ECF to cells

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6
Q

Diffusion of carbon dioxide is from…?

A

ICF out of cells

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7
Q

What percentage of oxygen in the blood is dissolved in plasma?

A

1.5%

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8
Q

How is the majority (98.5%) of oxygen carried in red blood cells?

A

On haemoglobin

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9
Q

What is Boyle’s law?

A

The pressure of a gas varies inversely with its volume

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10
Q

What is the primary muscle in inspiration?

A

The diaphragm

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11
Q

What happens to the diaphragm during expiration?

A

It relaxes, moves back to its original state

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12
Q

What are the active and passive processes?

A

Passive - breathing out

Active - breathing in

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13
Q

What happens during the active process (breathing in)?

A

Chest expands (lung volume increases) —— diaphragm contracts (pressure decreases) = air moves in

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14
Q

What happens during the passive process (breathing out) ?

A

Chest contracts (lung volume decreases) —— diaphragm relaxes (pressure increases) = air moves out

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15
Q

What are the 2 types of respirators?

A
  • negative pressure ventilator (iron lung)

- positive pressure system

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16
Q

What happens with a negative pressure ventilator?

A
  • helps assist or control breathing

- mimics physiological process of breathing by periodically altering pressure in the chamber

17
Q

What happens in a positive pressure system?

A
  • oxygen actively pushed into the lungs to create pressure difference
  • used when patient cannot breathe alone
  • useful for neonates, snoring, sleep apnoea, cardiac failure
18
Q

What are the mixture of gases in the air?

A
  • nitrogen 78%
  • oxygen 21%
  • other (carbon dioxide and water etc) 1%
19
Q

What is the net atmospheric pressure?

A

760 mmHg

20
Q

What is Dalton’s law?

A

Total pressure exerted by a mixture of gases is the sum of the partial pressures of the individual gases

21
Q

What is the partial pressure of oxygen in the atmosphere?

A

159 mmHg

22
Q

What is the partial pressure of carbon dioxide in the atmosphere?

A

0.15 mmHg

23
Q

Carbon dioxide has a much higher?

A

Solubility constant than oxygen - 20x higher

24
Q

What is Henry’s law?

A

Increase the partial pressure of a gas then more gas is dissolved

25
Q

How is carbon dioxide transported in the blood?

A
  • 75-80% transported as bicarbonate ion

- 20-25% transported bound to haemoglobin

26
Q

What is hypoxemia?

A

Low blood oxygen - defined as a decrease in the partial pressure of oxygen in the blood

27
Q

What is erythropoietin?

A

A hormone secreted mainly by the kidneys that stimulates bone marrow to produce more red blood cells which results in increased oxygen transport

28
Q

What are the causes of hypoxemia?

A
  • high altitude
  • respiratory failure
  • emphysema
  • COPD ( chronic obstructive pulmonary disease )
  • acute asthma
29
Q

What is decompression sickness?

A
  • nitrogen bubbles form when ascending too quickly from a dive
  • symptoms - itching skin and rashes, joint pain, sensory system failure, paralysis, brain embolism and death
30
Q

What is a hyperbaric chamber?

A
  • initiates slow ascend from diving depth to atmospheric pressure - nitrogen can come out of solution slowly
  • takes 3 - 4.5 hrs