Gallstones Flashcards

1
Q

What is cholecystitis?

A

Inflammation of the gallbladder

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2
Q

What is cholelithiasis?

A

Gallstones within the gallbladder

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3
Q

What is the name for gallstones which are implanted in the bile duct?

A

Choledocholithiasis

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4
Q

What is the name for infection of the bile duct?

A

Cholangitis

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5
Q

What two tests can be used to diagnostically investigate the biliary tract but can also be used therapeutically?

A

Endoscopic retrograde cholangiopancreatography

Percutaneous transhepatic cholangiography

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6
Q

What are the risk factors for developing cholelithiasis?

A
Female
Obese
Increasing age
Positive family history
Low fibre diet
Caucasian
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7
Q

What type of gallstone is usually solitary, oval and large (up to 3cm)?

A

Cholesterol stones

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8
Q

What is the appearance of bile pigment gallstones and what are these associated with?

A

Multiple stones, irregular and hard

Associated with chromic haemolysis

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9
Q

What type of gallstone is most common?

A

Mixed stones

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10
Q

Gallstones can form by the precipitation of cholesterol out of solution. How might this occur?

A

Cholesterol supersaturation due to high cholesterol levels (associated with high oestrogen levels - pregnancy, obesity) or low bile acid levels (e.g. after small bowel resection or with active chron’s)

Biliary stasis

Increased bilirubin secretion (increased haemolysis)

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11
Q

What are the symptoms of acute cholecystitis?

A
Pain
Fever
Vomiting
Nausea
Abdominal tenderness
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12
Q

How is acute cholecystitis treated?

A

Antibiotics
Analgesia
Elective cholecystectomy

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13
Q

What can be a complication of gallstones if they become impacted in the neck of the gallbladder?

A

Biliary colic

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14
Q

Post hepatic jaundice can be commonly caused by choledocholithiasis but also by…?

A

Cancer in the head of the pancreas which compresses on the common bile duct

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15
Q

What are the symptoms of post hepatic obstructive jaundice?

A
Pale stools
Dark urine
Yellow sclerae
Pruritus
Features of chromic liver disease
Abdominal tenderness
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16
Q

Gallstones can be a cause of post-hepatic jaundice. T/F?

A

True

17
Q

Obstructive jaundice, cholangitis and acute pancreatitis can present with choledocholithiasis. T/F?

A

True

18
Q

How would post hepatic obstructive jaundice as a result of choledocholithiasis be treated?

A

Antibiotics to treat cholangitis
ERCP - incision made at sphincter of oddi to increase the diameter of the duct and the stones are extracted using a balloon

19
Q

How is post hepatic jaundice as the result of pancreatic cancer treated?

A

ERCP to put in a stent to drain the bile and relieve the jaundice
Chemotherapy for the cancer can then take place