Gallbladder Pathology Flashcards
What is the most common cause of gallbladder wall thickening?
cholecystitis
Causes of gallbladder wall thickening
cholecystitis, adenomyomatosis, cancer, AIDS/HIV
Pericholecystic fluid is seen with?
acute cholecystitis
Gallbladder pathology is due to?
metabolic factors, stasis, inflammation
Choledochal cyst
outpouching of ductal walls due to relfuxing of enzymes
What is the most common form of a choledochal cyst?
fusiform dilatation of the CBD
Choledochal cyst type V is also known as?
Caroli’s Disease
Caroli’s disease
nonobstructive saccular dilatation of intrahepatic ducts
Caroli’s disease is more common in?
adults
Signs and symptoms of Caroli’s disease
jaundice, displacement of stomach and duodenum
Choledochal cysts are more common in?
children
Sludge
bile that coagulates; can lead to stones
Signs and symptoms of sludge
RUQ pain
What is the main cause of sludge?
prolonged fasting
Sonographic appearance of sludge
tends to layer, low level echoes, viscous, mobile, no shadow
Tumefactive sludge give the appearance of a?
pseudotumor
Sonographic appearance of tumefactive sludge
does not layer, sludge balls, mobile, echogenic, non shadowing
Sonographic appearance of cholelithiasis
mobile, echogenic foci, shadowing, gravity dependant
Which lab value is elevated with cholelithiasis?
ALP
6 Fs of cholelithiasis
Fat, Female, Fair, Forty, Fertile, Flatulent
WES sign
wall, echogenicity, shadow; gallbladder full of stones
With the WES sign, which part of the lumen is seen?
anterior
Bile duct obstruction causes an elevation in which lab values?
bilirubin and ALP
Signs and symptoms of bile duct obstruction
RUQ pain, jaundice, fever
Bile duct obstruction causes what sign?
double barrel, double duct
Choledocholithiasis can lead to?
cholangitis
Choledocholithiaisis causes an elevation in which lab values?
direct bilirubin, ALP, transaminase
The CBD is considered enlarged when it measures larger than?
7 mm
What is the most common inflammatory condition of the gallbladder?
acute cholecystitis
Signs and symptoms of acute cholecystitis
positive Murphy’s sign, RUQ pain, nausea, vomiting, fever
What lab values are elevated with acute cholesystitis?
ALP, leukocytosis, hyperbilirubinemia
Sonographic appearance of acute cholecystitis
wall thickening, enlarged gallbladder, may have stones, pericholecystic fluid, hyperemia
Acute acalculous cholecystitis
acute cholecystitis with no stones
Signs and symptoms of AAC
RUQ pain, positive Murphy’s sign, nausea, vomiting
Sonographic appearance of AAC
enlarged gallbladder with wall thickening, pericholecystic fluid
Empyema is also called?
Suppurative cholecystitis
Suppurative cholecystitis
pus in gallbladder
Empyema is more common in?
diabetics
Signs and symptoms of empyema
RUQ pain, fever, chills
Empyema can resemble?
sludge
Gallbladder perforation can result from?
acute cholecystitis
Gallbladder perforation usually occurs in which portion?
fundus
Signs and symptoms of gallbladder perforation
RUQ pain, vomiting, fever, leukocytosis, abnormal LFTs
Sonographic appearance of gallbladder perforation
defect in wall, complex fluid collection, irregular wall
Gangrenous cholecystitis
ischemic or necrotic wall due to lack of blood flow or infection
What kind of patients are more at risk for gangrenous cholecystitis?
diabetics
Sonographic appearance of gangrenous cholecystitis
thick irregular wall, gas or air in wall or lumen, ring down artifact
Emphysematous cholecystitis
gas in wall, lumen, pericholecystic space, or ducts from bacteria
Which patients are more at risk for emphysematous gallbladder?
men; diabetics
Sonographic appearance of emphysematous cholecystitis
gas appears as echogenic foci in wall or lumen, mobile, non gravity dependant, ring down or comet tail
Chronic cholecystitis is more common in?
women; elderly
What lab values are elevated with chronic cholecystitis?
ALP, AST, ALT, and bilirubin if jaundiced
Sonographic appearance of chronic cholecystitis
wall thickening, small gallbladder, cholelithiaiss
Bouveret syndrome
stones goes through gallbladder and into duodenum
Mirizzi syndrome
stone in cystic duct or neck causing compression on adjacent duct
Jaundice is also called?
icteric
Porcelain gallbladder
wall is calcified due to extensive inflammation
Porcelain gallbladder can lead to?
carcinoma
Porcelain gallbladder is more common in?
elderly women
Sonographic appearance of porcelain gallbladder
echogenic line with acoustic shadowing obscuring the gallbladder; gallstones are usually present
With dilated intrahepatic ducts, the obstruction is always ______ to the obstruction
proximal
Radicals cause an increase in which lab value?
ALP
Cholesterol polyp
benign growth of cholesterol
Sonographic appearance of a polyp
echogenic, fixed, no shadow, stalk
Differenc between adenoma and polyp
adenoma has no stalk
Primary gallbladder carcinoma begins as?
polyp, porcelain gallbladder, or chronic cholecystitis
Gallbladder carcinoma can be caused by METS from?
pancreatic cancer
Adenomyomatosis
excessive proliferations of surface epithelium with diverticula or outpouchings into lumen
Adenomyomatosis is also called?
Rokitansky-Aschoff sinuses
Adenomyomatosis is more common in?
women
Sonographic appearance of adenomyomatosis
comet tail with twinkle artifact; zig zag stripes, wall thickening
Strawberry gallbladder is also called?
cholesterolosis
Cholesterolosis
abnormal cholesterol deposits in wall; associated with gallstones
Strawberry gallbladder is more common in?
women
Sonographic appearance of cholesterolosis
fixed, no shadow, echogenic foci (seeds)
Courvousier gallbladder
palpable,enlarged, nontender, gallbladder in a jaundiced patient
Courvousier gallbladder is caused by?
extrinsic compression of CBD
Most common cause of Courvousier gallbladder
mass at pancreatic head
Hydropic gallbladder
abnormally distended gallbladder
Most common cause of hydropic gallbladder
stone in neck or cystic duct
Sonographic appearance of a hydropic gallbladder
round, distended, thin wall
Cholangiocarcinoma
primary malignancy in bile ducts
Klatskin tumor is a type of?
cholangiocarcinoma
Klatskin tumors cause dilation of the?
intrahepatic ducts
Klatskin tumors are located where?
at the junction of the right and left intrahepatic duct
Signs and symptoms of cholangiocarcinoma
icterus, palpable gallbladder, anorexia, fatigue
Cholangitis
inflammation or fibrosis of the ducts
Cholangitis causes an increase in which lab values?
ALP, AST, ALT, leukocytosis, and direct bilirubin with jaundice
Pneumobilia
gas/air in biliary tree; caused by surgery or infection
Pneumobilia causes what artifact?
dirty shadowing
Which type of gallbladder perforation is more common? What forms with it?
subacute; abscess