G-PROTEIN COUPLED RECEPTORS

Question 1

What are the activating receptors of G_{as (stimulatory) and their effect}

Answer 1

Glucagon

Parathyrin

ß-adrenergic

Stimulation of adenylate cyclase

Question 2

What are the activating receptors of G_{<strong>ai (inhibitory</strong>)} and their effects

Answer 2

Somatostatin

Alpha₂-adrenergic

Inhibition of adenylate cyclase

Question 3

what are the receptors of G_{aq (activating the PI cascade)} and their effects?

Answer 3

Vazopressin V1

Endotelin ET_A,B

Acetylcholine M₁

Alpha_1-adrenergic

Stimulation of phospholipase C

Question 4

what are/is the receptor(s) of G_at and its effect

(for transducin)

Answer 4

Rhodopsine

Stimulation of cGMP phosphodiesterase